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Duke Heart Week Ending August 22nd 2021

Transitions: McKinney Heading for New Role with Duke Life Point

Heather McKinney, MSN, RN, NE-BC, will be leaving Duke on August 27, 2021 for a position as ICU/PCU Director at a Duke LifePoint Hospital. Heather has worked in the Heart Center since 2002 in varying roles including as a staff nurse on 3100 and, for the past 13 years, as a Nurse Manager on 3100. During her time at Duke, Heather completed the American Organization for Nursing Leadership Nurse Manager fellowship, served on Duke University Health System and Duke University Hospital Committees, and had several presentations accepted at the American Association of Critical-Care Nurses National Teaching Institute conference.

Heather, who is widely known for ‘leading with her heart,’ has a passion for mentorship of staff and leaders and has supported the professional growth and development of many throughout the service line. She has nominated several leaders who won Great 100 or Friends of Nursing awards.

On behalf of the entire Duke Heart Leadership Team, we thank Heather for her dedication to our patients, the faculty and staff of Duke Heart, as well as to Duke University Hospital. She will certainly be missed.

Please join us in wishing her well in her new role!


Friede Abstract Selected for 2021 NCYIF

Congratulations to interventional cardiology fellow Kevin Friede – his abstract, A Gene Expression Signature Reflective of Exposure to Antiplatelet Therapy is Associated with Bleeding, has been selected for presentation at the 17th Annual Northwestern Cardiovascular Young Investigators’ Forum (NCYIF) being held at The Omni Chicago Hotel, October 14-16, 2021, in Chicago, IL. His mentor is Deepak Voora.

The event is presented by Northwestern University Feinberg School of Medicine and Creative Educational Concepts, Inc., and supported by an independent educational grant from AstraZeneca.

Congratulations Kevin!


Shout-out to Rymer, Freedman

A big shout-out this week for Jennifer Rymer and Neil Freedman from Jordan Pomeroy, who shared a note of gratitude with us:

Huge praise for Jenn Rymer and Neil Freedman for covering/switching shifts with me this week for CAD Night coverage. It brings significant peace of mind to know that I will be home to help my wife and kids while she recovers. I greatly appreciate my colleagues!”

Way to go, Jenn and Neil! We love the teamwork and support our colleagues show to one another.


Faculty/Fellows Gathering Held

Thanks to all who were able to join us on Thursday evening at Ponysaurus Brewing Company here in Durham to welcome our newest fellows to Duke!


Upcoming Events & Opportunities

September 9: MDEpiNet Predictable and Sustainable Implementation of National Cardiovascular Registries (PASSION CVR): Registry-Supported Prospective Trials: What are we missing? Part 1: Exploring Predicates and Lessons Learned. Noon – 5 p.m. ET. Virtual.

Join us for this Virtual Mini-Think Tank to explore opportunities, challenges, and lessons learned related to the uptake and adoption of registry-supported trials infrastructure! To register, please visit: https://duke.qualtrics.com/jfe/form/SV_b3Egi7WMPhsG8MS

Meeting Objectives:      

This collaborative, pre-competitive think tank aims to:

Part I (September 9th):

  • to provide a forum for frank discussion of predicates and “lessons learned” including operational barriers such as logistical, technical, fiscal and conceptual issues across key stakeholders
  • to develop themes for focused Working Groups going forward

Part II (TBD):

  • to target specific operational barriers with solution-oriented working groups tasked to define and develop concrete deliverables on a 12 month timeline in parallel with more aspirational deliverables of future import
  • to develop prospective study “use-case” opportunities leveraging prospective studies targeting regulatory- or clinical best practice- evidence collections


October 8: Duke Heart Failure Symposium: The Leading Edge of Heart Failure Management. Course directors are Richa Agarwal and Robert Mentz. 12 – 4:30 p.m. Zoom Webinar. To learn more and to register, please visit: http://duke.is/Q1sBtf


Have news to share?

If you have news to share with the Pulse readership, please contact Tracey Koepke, director of communications for Duke Heart at tracey.koepke@duke.edu. We would love to hear about your latest accomplishments, professional news, cool happenings, and any events or opportunities that may be of interest to our Duke Heart family. Please call with any questions: 919-681-2868. Feedback on Pulse is welcome and encouraged.


Duke Heart in the News:

August 12 — Adrian Hernandez


Fact Check-Animal Ivermectin should not be used on humans


August 12 — Mitchell Krucoff and E. Magnus Ohman


Conversations in Cardiology: Music in the Cath Lab?


Division of Cardiology Publications Indexed in PubMed August 12-18, 2021

Atwater BD, Li Z, Pritchard J, Greiner MA, Nabutovsky Y, Hammill BG. Early Increased Physical Activity, Cardiac Rehabilitation, and Survival After Implantable Cardioverter-Defibrillator Implantation. Circ Cardiovasc Qual Outcomes 2021;14(8):e007580. PM: 34284598.

Benjamin EJ, Al-Khatib SM, Desvigne-Nickens P, Alonso A, Djoussé L, Forman DE, Gillis AM, Hendriks JML, Hills MT, Kirchhof P, Link MS, Marcus GM, Mehra R, Murray KT, Parkash R, Piña IL, Redline S, Rienstra M, Sanders P, Somers VK, Van Wagoner DR, Wang PJ. Research Priorities in the Secondary Prevention of Atrial Fibrillation: A National Heart, Lung, and Blood Institute Virtual Workshop Report. J Am Heart Assoc 2021;10(16):e021566. PM: 34351783.

Brennan JM, Lowenstern A, Sheridan P, Boero IJ, Thourani VH, Vemulapalli S, Wang TY, Liska O, Gander S, Jager J, Leon MB, Peterson ED. Association Between Patient Survival and Clinician Variability in Treatment Rates for Aortic Valve Stenosis. J Am Heart Assoc 2021;10(16):e020490. PM: 34387116.

Colaco NA, Wang TS, Ma Y, Scherzer R, Ilkayeva OR, Desvigne-Nickens P, Braunwald E, Hernandez AF, Butler J, Shah SH, Shah SJ, Hsue PY. Transmethylamine-N-Oxide Is Associated With Diffuse Cardiac Fibrosis in People Living With HIV. J Am Heart Assoc 2021;10(16):e020499. PM: 34365799.

Cremer PC, Wang TKM, Rodriguez LL, Lindman BR, Zhang Y, Zajarias A, Hahn RT, Lerakis S, Malaisrie SC, Douglas PS, Pibarot P, Svensson LG, Kapadia S, Leon MB, Jaber WA. Incidence and Clinical Significance of Worsening Tricuspid Regurgitation Following Surgical or Transcatheter Aortic Valve Replacement: Analysis From the PARTNER IIA Trial. Circ Cardiovasc Interv 2021;14(8):e010437. PM: 34266311.

Dehghani P, Cantor WJ, Wang J, Wood DA, Storey RF, Mehran R, Bainey KR, Welsh RC, Rodés-Cabau J, Rao S, Lavi S, Velianou JL, Natarajan MK, Ziakas A, Guiducci V, Fernández-Avilés F, Cairns JA, Mehta SR. Complete Revascularization in Patients Undergoing a Pharmacoinvasive Strategy for ST-Segment-Elevation Myocardial Infarction: Insights From the COMPLETE Trial. Circ Cardiovasc Interv 2021;14(8):e010458. PM: 34320839.

Dungan JR, Qin X, Hurdle M, Haynes CS, Hauser ER, Kraus WE. Corrigendum: Genome-Wide Variants Associated With Longitudinal Survival Outcomes Among Individuals With Coronary Artery Disease. Front Genet 2021;12:726466. PM: 34386044.

Eliya Y, Whitelaw S, Thabane L, Voors AA, Douglas PS, Van Spall HGC. Temporal Trends and Clinical Trial Characteristics Associated With the Inclusion of Women in Heart Failure Trial Steering Committees: A Systematic Review. Circ Heart Fail 2021;14(8):e008064. PM: 34281362.

Giugliano RP, Gencer B, Wiviott SD, Park JG, Fuchs CS, Goessling W, Musliner TA, Tershakovec AM, Blazing MA, Califf R, Cannon CP, Braunwald E. Prospective Evaluation of Malignancy in 17,708 Patients Randomized to Ezetimibe Versus Placebo: Analysis From IMPROVE-IT. JACC CardioOncol 2020;2(3):385-396. PM: 34396246.

Gomez JA, Payne A, Pratt RE, Hodgkinson CP, Dzau VJ. A role for Sfrp2 in cardiomyogenesis in vivo. Proc Natl Acad Sci U S A 2021;118(33):e2103676118. PM: 34380738.

Greene SJ, Choi S, Lippmann SJ, Mentz RJ, Greiner MA, Hardy NC, Hammill BG, Luo N, Samsky MD, Heidenreich PA, Laskey WK, Yancy CW, Peterson PN, Curtis LH, Hernandez AF, Fonarow GC, O’Brien EC. Clinical Effectiveness of Sacubitril/Valsartan Among Patients Hospitalized for Heart Failure With Reduced Ejection Fraction. J Am Heart Assoc 2021;10(16):e021459. PM: 34350772.

Melloni C, Slovin SF, Blemings A, Goodman SG, Evans CP, Nilsson J, Bhatt DL, Zubovskiy K, Olesen TK, Dugi K, Clarke NW, Higano CS, Roe MT. Cardiovascular Safety of Degarelix Versus Leuprolide for Advanced Prostate Cancer: The PRONOUNCE Trial Study Design. JACC CardioOncol 2020;2(1):70-81. PM: 34396210.

Moll-Bernardes R, de Sousa AS, Macedo AVS, Lopes RD, Vera N, Maia LCR, Feldman A, Arruda GDAS, Castro MJC, Pimentel-Coelho PM, de Albuquerque DC, de Paula TC, Furquim TAB, Loures VA, Giusti KGD, de Oliveira NM, De Luca FA, Kotsugai MDM, Domiciano RAM, et al. IL-10 and IL-12 (P70) Levels Predict the Risk of Covid-19 Progression in Hypertensive Patients: Insights From the BRACE-CORONA Trial. Front Cardiovasc Med 2021;8:702507. PM: 34386533.

Paul S, Wong M, Akhabue E, Mehta RC, Kramer H, Isakova T, Carnethon MR, Wolf M, Gutiérrez OM. Fibroblast Growth Factor 23 and Incident Cardiovascular Disease and Mortality in Middle-Aged Adults. J Am Heart Assoc 2021;10(16):e020196. PM: 34387090.

Piccini JP, Dufton C, Carroll IA, Healey JS, Abraham WT, Khaykin Y, Aleong R, Krueger SK, Sauer WH, Wilton SB, Rienstra M, van Veldhuisen DJ, Anand IS, White M, Camm AJ, Ziegler PD, Marshall D, Bristow MR, Connolly SJ. Bucindolol Decreases Atrial Fibrillation Burden in Patients With Heart Failure and the  Arg389Arg Genotype. Circ Arrhythm Electrophysiol 2021;14(8):e009591. PM: 34270905.

Szarek M, Bhatt DL, Steg PG, Cannon CP, Leiter LA, McGuire DK, Lewis JB, Riddle MC, Voors AA, Metra M, Lund LH, Komajda M, Testani JM, Wilcox CS, Ponikowski P, Lopes RD, Banks P, Tesfaye E, Ezekowitz JA, Verma S, Pitt B. Effect of Sotagliflozin on Total Hospitalizations in Patients With Type 2 Diabetes and Worsening Heart Failure : A Randomized Trial. Ann Intern Med 2021;174(8):1065-1072. PM: 34152828.

Weissler EH, Osazuwa-Peters OL, Greiner MA, Hughes GC, Long CA, Vemulapalli S, Patel MR, Jones WS. National trends in repair for type B aortic dissection. Clin Cardiol 2021;44(8):1058-1068. PM: 34173677.


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