A large number of sequences showing evolutionary relatedness to the kinesin motor domain have now been deposited into the databases. Based on sequence similarities, most of these proteins can be assigned to one of fourteen families or groups. The kinesin families or groups have recently been renamed (see Nomenclature). The new names of the families (with the previous names in parentheses) are: Kinesin-1 (KHC or kinesin heavy chain), Kinesin-2(KRP85/95), Kinesin-3 (Unc104/Kif1), Kinesin-4 (Chromokinesin/KIF4), Kinesin-5 (BimC), Kinesin-6 (MKLP1), Kinesin-7 (CENP-E), Kinesin-8 (KIP3), Kinesin-9, Kinesin-10, Kinesin-11, Kinesin-12, Kinesin-13 (MCAK/KIF2), and Kinesin-14 (C-terminal motor). The Orphan kinesins are those that have been analyzed for relatedness to other kinesin proteins, but are as yet ungrouped. The new family names are shown in the table below with the former family names in parentheses. The table below contains both complete and partial motor domain sequences.
Key to labels used in the table: Entries highlighted in yellow have not yet been analyzed to determine the relatedness of the protein to other kinesin proteins. These sequences are denoted TBD, indicating that the family assignment has yet to be determined. Partial motor domain sequences are indicated in the table with an F (for fragment). Entries for which genomic sequence is available are indicated by the label G. The text entries in red are likely to change. Uncertain indicates that these entries may be kinesin motor domain homologues, but they lack crucial amino acid residues that would make them functional kinesins. In some cases, there may be errors in the predicted sequences.
This version of the table is broken up by organism to reduce loading time. The sequence table for species with six or more known kinesin proteins will appear in a separate window when you click on the organism’s name.
|
Organism |
Protein name |
GenBank ID |
Protein ID |
SwissProt |
Family |
length |
also known as |
|
|---|---|---|---|---|---|---|---|---|
| Arabidopsis thaliana | 61 proteins for this organism in subtable. | |||||||
| Aspergillus nidulans (Emericella nidulans) |
AnBimC | M32075 | 114988 | P17120 | Kinesin-5 (BimC) | 1184 | ||
| AnKlpA | X64603 | 125477 | P28739 | Kinesin-14 (C-term) | 770 | |||
| AnKipA | XP749137 | 70987448 | Q4WG42 | Kinesin-7 | 955 | |||
| AnKipB | CAF06507 | 40974913 | Q704T4 | Kinesin-8 | 989 | |||
| AnKinA | AJ291452 | 12044815 | TBD | 927 | ||||
| Bombyx mori (silkworm) |
BmKrp | D21206 | 1170673 | P46874 | Kinesin-5 (BimC) | F | 378 | |
| Candida albicans | CaKrp | AL033502 | 3859666 | Orphan (ungrouped) | G | 665 | ||
| Caenorhabditis elegans | 19 proteins for this organism in subtable. | |||||||
| Chlamydomonas rheinhardtii | CrFLA10 | L33697 | 1169693 | P46869 | Kinesin-2 (KRP85/95) | 786 | ||
| CrKlp1 | X78589 | 1170672 | P46870 | Orphan (ungrouped) | 776 | |||
| CrIar1 | Ab112468 | Q7X931 | TBD | 1009 | ||||
| Cricetulus griseus (Chinese hamster) |
CgCHO1 | X83575 | 2119281 | Kinesin-6 (MKLP1) | 953 | |||
| CgCHO2 | X83576 | 683538 | Q60443 | Kinesin-14 (C-term) | 622 | |||
| CgMCAK | U11790 | 4521322 | P70096 | Kinesin-13 (MCAK/KIF2) | 718 | |||
| Cyanophora paradoxa | CpKlp | AF219229 | 11991837 | TBD | F | 158 | ||
| Cylindrotheca fusiformis | CfDSK1 | U51680 | 2497529 | Q39493 | Kinesin-13 (MCAK/KIF2) | 624 | ||
| Danio rerio | 7 proteins for this organism in subtable. | |||||||
| Dictyostelium discoideum | 14 proteins for this organism in subtable. | |||||||
| Drosophila melanogaster | 24 proteins for this organism in subtable. | |||||||
| Drosophila yakuba | Dy2A12 | AF005854 | 2459906 | TBD | F | 501 | ||
| Gallus gallus (chicken) |
GgChrkin | U18309 | 1079393 | Kinesin-4 (Chromokinesin) | 1225 | |||
| Homo sapiens | 45 proteins for this organism in subtable. | |||||||
| Leishmania chagasi | LcKin | L07879 | 1170665 | P46865 | Orphan (ungrouped) | 955 | ||
| Leishmania major | 9 proteins for this organism in subtable. | |||||||
| Loligo pealii (squid) |
LpKHC | J05258 | 125415 | P21613 | Kinesin-1 (KHC) | 967 | ||
| Lymantria dispar (gypsy moth) |
LdKlp1 | AF338870 | 13173401 | TBD | F | 143 | ||
| Monodelphis domestica | MdKrp | AF005902 | 2253297 | TBD | F | 133 | ||
| Morone saxatilis | 8 proteins for this organism in subtable. | |||||||
| Mus musculus | 47 proteins for this organism in subtable. | |||||||
| Nectria haematococca | NhKin1 | U86521 | 1839174 | Kinesin-1 (KHC) | G | 929 | ||
| NhKrp1 | AF102992 | 4092763 | Kinesin-14 (C-term) | G | 802 | |||
| NhKrp2 | AF102993 | 4092765 | TBD | F | 1024 | |||
| Neurospora crassa | NcKHC | L47106 | 1346380 | P48467 | Kinesin-1 (KHC) | 926 | ||
| Nc17E5.250 | AL513467 | 12718289 | TBD | G | 647 | |||
| Nicotiana tabacum | NtKCBP | U52078 | 1491931 | Kinesin-14 (C-term) | 1265 | |||
| NtKRP125 | D83711 | 2582971 | O23826 | Kinesin-5 (BimC) | 1006 | |||
| Oryza sativa | OsP0006C01.8 | AP002744 | 11761076 | TBD | G | 707 | ||
| OsP0504D03.21 | AP002970 | 13161377 | TBD | G | 954 | |||
| OsPAKRP1 | AF210816 | 8745341 | TBD | F | 817 | |||
| Paracentrotus lividus | Plboursin | AJ293506 | 12055369 | TBD | G | 1081 | ||
| Plasmodium falciparum | 7 proteins for this organism in subtable. | |||||||
| Rattus norvegicus | 11 proteins for this organism in subtable. | |||||||
| Saccharomyces cerevisiae | 6 proteins for this organism in subtable. | |||||||
| Schizosaccharomyces pombe | 9 proteins for this organism in subtable. | |||||||
| Solanum tuberosum (potato) |
PoKCBP | L46702 | 1369852 | Kinesin-14 (C-term) | 1265 | |||
| Strongylocentrotus purpuratus (sea urchin) |
SpKHC | X56844 | 10270 | P35978 | Kinesin-1 (KHC) | 1031 | ||
| SpKRP85 | L16993 | 1170653 | P46872 | Kinesin-2 (KRP85/95) | 699 | KIN2A | ||
| SpKRP95 | U00996 | 1170652 | P46871 | Kinesin-2 (KRP85/95) | 742 | KIN95 | ||
| SpKinC | AF191095 | 6166459 | Kinesin-14 (C-term) | 1624 | ||||
| Syncephalastrum racemosum | SyKin1 | AJ225894 | 2879849 | O43093 | Kinesin-1 (KHC) | 935 | ||
| Tetrahymena thermophila | TtKin1 | AJ244020 | 5640166 | Q9U0D5 | Kinesin-2 (KRP85/95) | 735 | ||
| TtKin2 | AJ244021 | 5679735 | Q9U921 | Kinesin-2 (KRP85/95) | 697 | |||
| Trypanosoma brucei | TrKIFC1 | AF319546 | 11245496 | TBD | 820 | |||
| Ustilago maydis | UmKin1 | U92844 | 2062750 | Orphan (ungrouped) | 1459 | |||
| UmKin2 | U92845 | 2062752 | Kinesin-1 (KHC) | 968 | ||||
| Volvox carteri | VcInvA | AB112467 | Q7X932 | TBD | 1003 | |||
| Xenopus laevis | 13 proteins for this organism in subtable. | |||||||
View the Kinesin heavy chain signature in the PRINTS database.
View the Kinesin motor domain signature in the ProSite database.
View the Kinesin motor domain in the BLOCKS database.
View the kinesin entry in the Pfam database.
Go to the Kinesin Motor Domain Alignment.
Go to the phylogenetic tree derived from kinesin motor domain sequences.
If you use diagrams, trees, or sequence alignments from the Kinesin site, we ask that you cite either the home page and authors, or the appropriate source publication in your work.
Copyright 1996-2007. All rights reserved
Created 7 July 1996 20:00 GMT
Modified 20 December 2017 20:30 GMT
