| Species/protein | Molecular mass (kDa) | Motor polarity & velocity | Subcellular localization | Comments |
|---|---|---|---|---|
| A. thaliana FCA0.24 | ND | ND | ||
| A. thaliana FCA1.2 | ND | ND | ||
| A. thaliana F25I16.11 | ND | ND | ||
| A. thaliana T9C5.240 | 91 | ND | ND | |
| A. thaliana T19F6 | ND | ND | ||
| A. thaliana T20H2.17 | ND | ND | ||
| C. elegans C06G3.2 | ND | ND | ||
| D. melanogaster Klp54D | ND | |||
| D. melanogaster Klp67A | 92 | ND | ||
| D. melanogaster Nod | 74 | ND | Meiotic chromosomes | Binds DNA, may be monomeric |
| H. sapiens KIF9 | ND | |||
| H. sapiens KIF18 | ND | |||
| H. sapiens FLJ3730 | ND | |||
| H. sapiens KLP6Q27 | ND | |||
| H. sapiens KLP7 | ND | |||
| P. falciparum MAL1P2.n | ND | |||
| P. falciparum MAL3P7.1 | 138 | ND | ||
| L. chagasi Kin | 230 | ND | ND | |
| L. major L6586 | ND | ND | ||
| S. cerevisiae Kip2 | ND | ND | ||
| S. cerevisiae Smy1 | 74 | ND | ND | Role in secretion overlapping that of a myosin |
| S. pombe BC1604 | ND | ND | ||
| U. maydis Kin1 | 157 | ND | ND | |
| X. laevis Klp2 | 159 | Plus, 2-4 µm/min | Centrosomes, spindle poles | Required for centrosome separation and spindle bipolarity |
1 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550
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AtFCA0.24 PPRKLRSAKENAPPLDRNTSTPDHRSMRMKNPLPPRPPPS----------------NPLKRKLSAETATESGFSDSG----------VKEQMFQLVGAPLVENCLSGFNSSVFAYGQTGSGKTYTMWGP-ANGLLEEHLCGDQRGLTPRVFERLFARIKEVMPGFVQFVVLTLNKSSMLKGNSITNVGAHYSRFSDWLHYISLDDLQRANNRPTGPKPEKPDGKHGVHRFSLMCHQIREDVKS----------------------GVYVENLTEEYVKNLTDVSQLLI--------------------------------------------------------------------KGLGNRRTGATSVNTESSRSHCVFTCVVESR-----CKNVADGLSSFKTSRINLVDLAGSERQKSTG-AAGERLKEAGNINRSLSQLGNLINILAEIS---------------------------QTGKPRHIPYRDSRLTFLLQES-LGGNAKLAMVCAVSPSQR--SETFSTLRFAQRA-KAI-QNKAVVN AtFCA0.24
AtFCA1.2 KTPNPDGSKDPSPPEHPVEVIGRIRDYPDRKEKSPSILQV--------NTDNQTVRVRADVGYRDFTLDGVSFSEQE----------GLEEFYKKFIEERIKGVKVGNKCTIMMYGPTGAGKSHTMFGC-----------GKEPGIVYRSLRDILGDSDQDGV------------------------------------------------------------------------------------------------------TFVQVTVLEVYNEEIYDLLSTNS------------------------SNNLGIGWPKGASTKVRLEVMGKKAKNASFISGTEAGKISKEIVKVEKRRIVKSTLCNERSSRSHCIIILDVPTV-----------------GGRLMLVDMAGSENIDQAGQTGFEAKMQTAKINQGNIALKRVVESIANGD--------------------------------SHVPFRDSKLTMLLQDSFEDDKSKILMILCASPDPKEMHKTLCTLEYGAKA-KCIVRGSHTPN AtFCA1.2
AtT19F6 GEEKILVSVRVRPLNEKEKTRNDRCDWECINDTTIICKFH-------------------NLPDKSSYTFDKVFGFEC----------PTKQVYDDGAKEVALCVLSGINSSIFAYGQTSSGKTYTMSGI-----------------TEFAMDDIFAYIDKHKQERK---------------------------------------------------------------------------------------------------FTLKFSAMEIYNEAVRDLLCEDS---------------------------------STPLRLLDDPERGTVVEKLREETLRDRSHLEELLSICETQRKIGETSLNEISSRSHQILRLTIESS-----SQQFSPESSATLAASVCFVDLAGSERASQTL-SAGSRLKEGCHINRSLLTLGTVIRKLSKGK-------------------------------NGHIPYRDSKLTRILQNS-LGGNARTAIICTMSPARSHLEQSRNTLLFATCA-KEV-TTNAQVN AtT19F6
CeC06G3.2 MSQYIKCYGRVRPSARLGAPSESLFVGGRVVTIETDNGSK-------------------------RYELHHIFDSSS----------SQEDVFGTVAKKIVEDCVEGYNGTVFAYGQTGSGKTHTMLGP-----CDSWTDQELMGLIPRSVEHVFQHLDTKAKECQKLT------------------------------------------------------------------------------------------------FSVSVEFVELYNEVIYDLLNAKN------------------------------------KVQLRDSGKDIQLVGALSKNVDNPLDLMHLVQKGWQERSTGSTAMNAESSRSHALLIIRIKTQ-------ERTGELVKERSSILNLVDLAGSERQTHTK-SSGDRLKEATNINSSLTVLGRCIRLLADPS-----------------------------KAKGHVPYRDSHLTHILKNS-LGGNSKTAVIVNMHPDRDFAQESNSTLMFAQSC-TMI-MNIATRN CeC06G3.2
DmKlp54D PEDNINVVVRVRPLNDKEKRDRHGSTLQFPGNGQVILEGNDV---------GQKRSHNRDSVRVFTYNVVFEPGATQ-----------EDILDYSGIKRIIEMGIEGFSCTAFCYGQTGSGKTHTLTGPPDLFVGKPNPKDPRHGLIFRSFLYLFQLIKNRKDVN----------------------------------------------------------------------------------------------------YVLKASFMEIYNERVIDLLNPGS-------------------------------ARKPLAVRWSKKSGGFFVENLFTVDCEELDDLLAVLEEGMRNRAVGSHAMNDHSSRSHTILTVHILSDQ------QTDGGVFLSKHGKINFVDLAGSELTKKTM-SEGKTLEEANNINKSLMVLGYCISSLSDSK-----------------------------KRTGHIPYRDSQLTKLLADS-LAGNGVTLMIACVSPAHYNHAETLNTLRYASRA-KRI-RTKPVIK DmKlp54D
DmNod GAKLSAVRIAVREAPYRQFLGRREPSVVQFPPWSDGKSLI---------------------VDQNEFHFDHAFPATI----------SQDEMYQALILPLVDKLLEGFQCTALAYGQTGTGKSYSMGMT-----PPGEILPEHLGILPRALGDIFERVTARQENNKDA-------------------------------------------------------------------------------------------------IQVYASFIEIYNEKPFDLLGST----------------------------------------PHMPMVAARCQRCTCLPLHSQADLHHILELGTRNRRVRPTNMNSNSSRSHAIVTIHVKSK---------------THHSRMNIVDLAGSEGVRRTG-HEGVARQEGVNINLGLLSINKVVMSMAAGH--------------------------------TVIPYRDSVLTTVLQAS-LTAQSYLTFLACISPHQCDLSETLSTLRFGTSA-KKL-RLNPMQV DmNod
LcKIN EAERVKVSVRVRPLNERENNAPEGTKVTVAAKQAAAVVTV--KVLGGSNNSGAAESMGTARRVAQDFQFDHVFWSVETPDACGATPATQADVFRTIGYPLVQHAFDGFNSCLFAYGQTGSGKTYTMMGA-----DVSALSGEGNGVTPRICLEIFARKASVEAQGHSR-------------------------------------------------------------------------------------------------WIVELGYVEVYNERVSDLLGKRK-------------------------KGVKGGGEEVYVDVREHPSRGVFLEGQRLVEVGSLDDVVRLIEIGNGVRHTASTKMNDRSSRSHAIIMLLLREE-RTMTTKSGETIRTAGKSSRMNLVDLAGSERVAQSQ-VEGQQFKEATHINLSLTTLGRVIDVLADMA------------------------TKGAKAQYSVAPFRDSKLTFILKDS-LGGNSKTFMIATVSPSALNYEETLSTLRYASRA-RDI-VNVAQVN LcKIN
LmL6586 MEGQERRSVVEMTNTKTILLDPKDGWAPKAQFDFDASLW----------------SIPPTHRIVHTFQ-DTKHKTYA----------TQKDVYNLIAKDLVPHVFNGFNSCILTYGQTGSGKTYTMMGL--YDPNASCGGDGEEGIIPRVSNDIFIILKERMEEEAK-----------------------------------------------------------------------------------------TRPPRDRTKFRVEVSFVEIYMERVRDLLDPAL-------------------------RHTRSNEHLQDARIRQDPYSGPFVEGVTKYEVENWTQCCTLLERGSQHRTTCATAVHNQSSRSHAIFQLTVVQEQVVPGNNKYALPAFKTQAGRINLVDLAGSERGGFQD-----YVKESAAINTSLLALRRVIDNLTERQ-----------NMLMEMAEAEITGKHYQERPLPQVPFRDSVLTWLLSDS-IGGNARTTMVATLSPLVKNYADTLATLQWSSRA-RNL-VTLVKMN LmL6586
ScKIP2 DTYTGSITVTIRPKPRSVGTSRDHVGLKSPRYSQPRSNSHHGSNTFVRDPWFITNDKTIVHEEIGEFKFDHVFASHC----------TNLEVYERTSKPMIDKLLMGFNATIFAYGMTGSGKTFTMSGN-----------EQELGLIPLSVSYLFTNIMEQSMNGDKK-------------------------------------------------------------------------------------------------FDVIISYLEIYNERIYDLLESGLEESGSRISTPSRLYMSKS----------NSNGLGVELKIRDDSQYGVKVIGLTERRCESSEELLRWIAVGDKSRKIGETDYNARSSRSHAIVLIRLTSTN---------VKNGTSRSSTLSLCDLAGSERATGQE-----RRKEGSFINKSLLALGTVISKLSADKQMNSVGSNIPSPSASGSSSSSGNATNNGTSPSNHIPYRDSKLTRLLQPA-LSGDSIVTTICTVDTRNDAAAETMNTLRFASRA-KNV-ALHVSKK ScKip2
ScSMY1 EPCHIEVILRAIPEKGLQNNESTFKIDPYENTVLFRTNNP---------------LHETTKETHSTFQFDKVFDANA----------TQEDVQKFLVHPIINDVLNGYNGTVITYGPSFSGKSYSLIGS-----------KESEGILPNICKTLFDTLEKNEETKGDS-------------------------------------------------------------------------------------------------FSVSVLAFEIYMEKTYDLLVPLP-------------------------------ERKPLKLHRSSSKMDLEIKDICPAHVGSYEDLRSYIQAVQNVGNRMACGDKTERSRSHLVFQLHVEQR---------NRKDDILKNSSLYLVDLHGAEKFDKRT-ESTLSQDALKKLNQSIEALKNTVRSLSMKE----------------------RDSAYSAKGSHSSAYRESQLTEVLKDS-LGGNRKTKVILTCFLS--NVPTTLSTLEFGDSI-RQI-NNKVTDN ScSMY1
SpoBC1604 VGSGIITSIRIRPIGKNQGVWSHGKLSNDPYGREYIRQQT----------------STSSSTIQQEYLFNNVFGMES----------KNYDIYKRSVKSVVRNVFSGYNGIVFAYGMTGTGKTYSMQGT-----------ENEPGIIPLAMNDLFEMVENNSDDDT---------------------------------------------------------------------------------------------------FQIRISYLEIYNERIRDLIGNSD----------------------------------EEPRIRENASGEVNVTPLTRVLVTSPEEVSQVIEQCNAIRKTAATDFNTYSSRSHAILQVFLIRNN---------PTAHTSQISSLSLVDLAGSERASAHH----ERRKEGAFINKSLLTLGTVISRLSAAA------------------------NPSLTSNSGHIPYRESKLTRLLQQS-LSGQSQISLLATISIESNHTMETTNTLKFASRA-QNL-PQDIRQA SpoBC1604
UmKin1 PTEHHPAIAKRTTSSERAGAGASIAAAPSSHDLDHEDPTS----------------------STYHFQFDKLITGAQ----------TTDDMYHSHIAPVVRAAVEGYNGTVFAYGQTGSGKTHTMSGS-----------DAEPGVIPRAVEQIFQMIKDEPDRE----------------------------------------------------------------------------------------------------FLLRVSYLEIYNETLKDLLAPLPPLTGSTGSSLQTTDRPASPIKGGSSHAAGQSQSCTLRIIEDQKSSRVIITGLREEIVTDANTVLCLIQRGQDERHVGATDWNERSSRSHCVFQLTIESR------SPAPSASKEVRISQLNLIDLAGSERAA----SQAERRKEGAFINKSLLTLGTVIGKLTEPV----------------------------ENGDAHIPYRDSKLTRILQTS-LSGNARIAVICTLSPDTEHANETLSTLKFGKRC-KLV-VTTAKKG UmKin1
Xlklp2 EEDAIKVFVRIRPPVEGTLTGVDGEQGLCLTALSSTTIRL------------------HSKPEPKMFTFDHVANVDT----------NQESVFSSVAKNIVESCMNGYNGTIFAYGQTGSGKTFTMLGP----SESDNFTHNLRGVIPRSFEYLFFLINREKEKAGEGKS-----------------------------------------------------------------------------------------------FLCKCSFIEIYNEQIFDLLDSAS----------------------------------AGLFLREHIKKGVFVVGAVEQVVTSAAEAYQVLSMGWRNRRVASTSMNRESSRSHAVFTVTIESM-------EKTNDLVNIRSSQLNLVDLAGSERQKDTQ-TEGVRLKEAGSINRSLSCLGQVITALVDVA----------------------------NGRQRHICYRDSKLTFLLRDS-LGGNAKTFYIANVHPGSKCFGETLSTLQFAQRA-KLI-KNKAVVN Xlklp2
If you use diagrams or sequence alignments from the Kinesin site, we ask that you cite either the home page and authors, or the appropriate source publication in your work.
Copyright 1996-2005. All rights reserved.
Created 16 July 1996 00:00 GMT
Modified 25 January 2005 7:33 GMT
