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Animal Models and Their Role in Imaging-Assisted Co-Clinical Trials

This overview paper describes the ten co-clinical trials of investigators from eleven institutions who are supported by the CIRP initiative and are members of the Animal Models and Co-clinical Trials (AMCT) Working Group. Examples of MRI and micro-CT images in … Continue reading

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QIAL papers @ CT Meeting 2022

1. C. Badea, D. Clark, A. Alphin, J. C. Ramirez-Giraldo, P. Bhandari, Y. Mowery, K. Ghaghada. Co-clinical photon counting CT research for multi-contrast imaging. Proceedings Volume 12304, 7th International Conference on Image Formation in X-Ray Computed Tomography; 123040G (2022)  https://doi.org/10.1117/12.2646399 2. … Continue reading

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Preclinical implementation of a clinical trial

This study aimed to investigate whether adding neoadjuvant radiotherapy (RT), anti-programmed cell death protein-1 (PD-1) antibody (anti-PD-1), or RT + anti-PD-1 to surgical resection improves disease-free survival for mice with soft tissue sarcomas (STS). The paper has been included in … Continue reading

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Deep learning based multimodal segmentation of acute ischemic stroke lesions in the human brain

Hae Sol Moon, Lindsay Heffron, Ali Mahzarnia, Barnabas Obeng-Gyasi, Matthew Holbrook, Cristian T. Badea, Wuwei Feng, Alexandra Badea, Automated multimodal segmentation of acute ischemic stroke lesions on clinical MR images, Magnetic Resonance Imaging, 2022, ISSN 0730-725X, https://doi.org/10.1016/j.mri.2022.06.001.

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Imaging Biomarkers for Alzheimer’s Disease Using Magnetic Resonance Microscopy

Book Chapter: Alexandra Badea, Jacques A Stout, Robert J Anderson, Gary P Cofer. Imaging Biomarkers for Alzheimer’s Disease Using Magnetic Resonance Microscopy in Magnetic Resonance Microscopy: Instrumentation and Applications in Engineering, Life Science, and Energy Research. Sabina Haber-Pohlmeier (Editor), Bernhard … Continue reading

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Our QIAL contributions at SPIE Medical Imaging 2022

A. J. Allphin, D. P. Clark, A. Badea, and C. T. Badea “Anatomical and functional cardiac PCCT imaging pipeline for characterization of Apolipoprotein E mouse models“, Proc. SPIE 12036, Medical Imaging 2022: Biomedical Applications in Molecular, Structural, and Functional Imaging, 120360Z (4 April 2022); https://doi.org/10.1117/12.2611806 … Continue reading

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Photon counting CT and radiomics for cancer imaging

Allphin, A. J., Y. M. Mowery, K. J. Lafata, D. P. Clark, A. M. Bassil, R. Castillo, D. Odhiambo, M. D. Holbrook, K. B. Ghaghada and C. T. Badea (2022). “Photon Counting CT and Radiomic Analysis Enables Differentiation of Tumors … Continue reading

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Congratulations to Dr. Darin Clark!

Congratulations to our QIAL member, Dr. Darin Clark, for his promotion  to  Assistant Professor in Radiology!

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Alzheimer’s Risk in Women

Female-Led Team Investigates Increased Alzheimer’s Risk in Women https://bassconnections.duke.edu/about/news/female-led-team-investigates-increased-alzheimers-risk-women

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Book Section on Micro X-ray Computed Tomography

Badea, Cristian. “Principles of Micro X-ray Computed Tomography.” In Molecular Imaging Principles and Practice, edited by Brian Ross and Sanjiv Sam Gambir, 1:47–64. Academic Press, 2021. https://doi.org/10.1016/B978-0-12-816386-3.00006-5.

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