We developed a multiscale method to map how aging and APOE risk factors impact brain connections in Alzheimer’s. Frontal & occipital bundles emerge as key predictors. Early detection might start with olfactory memory.
Stout, J., Anderson, R. J., Mahzarnia, A., Han, Z. Y., Beck, K., Browndyke, J., Johnson, K., O’Brien, R. J., & Badea, A. (2025). Mapping the impact of age and APOE risk factors for late onset Alzheimer’s disease on long range brain connections through multiscale bundle analysis. Brain Structure and Function, 230, 45. https://doi.org/10.1007/s00429-025-02905-9
