Category Archives: Uncategorized

Hae Sol Moon Defends PhD on Alzheimer’s Modeling

Congratulations! Dr. Hae Sol Moon has successfully defended his PhD on “Integrative Modeling of Alzheimer’s Disease Risk”.

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Celebrating Dr. Alex Allphin’s PhD Defense!

Huge congratulations to Dr. Alex Allphin on a successful PhD defense! A key member of our QIAL lab, Alex’s work has pushed the boundaries of imaging science.

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Mapping Exercise-Induced Brain Changes in Alzheimer’s Disease

Voluntary & enforced exercise drive distinct brain changes in Alzheimer’s models.MRI reveals how emotion, memory, & motor circuits adapt—showing exercise’s neuroprotective power. Badea A, Mahzarnia A, Reddy D, et al. Neuroimaging biomarkers of neuroprotection: Impact of voluntary vs. enforced exercise … Continue reading

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APOE-Dependent Cardiac Response to Exercise in Mice via PCCT

This study investigates the impact of exercise on cardiac function across different APOE genotypes in mice using low-dose cardiac photon-counting micro-CT and deep learning-based segmentation. Results show significant, genotype-dependent improvements in cardiac performance, with the largest effects observed in APOE3 … Continue reading

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QIAL Contributions to SPIE Medical Imaging 2025

Advancing Preclinical and AI-Driven Imaging  with our Work presented at SPIE Medical Imaging 2025: Deve​lopment of a virtual photon-counting micro-CT imaging platform for preclinical cancer studiesNadkarni R, Clark D, Allphin A, Qi Y, Mowery Y, Segars W, Badea CT.Presented on … Continue reading

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Nanoparticle Contrast Agents for Photon-Counting Computed Tomography

Our  review article is published:Devkota L, Bhavane R, Badea CT, Tanifum EA, Annapragada AV, Ghaghada KB. Nanoparticle Contrast Agents for Photon-Counting Computed Tomography: Recent Developments and Future Opportunities. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2025 Jan-Feb;17(1):e70004. doi: 10.1002/wnan.70004. PMID: 39948059. https://wires.onlinelibrary.wiley.com/doi/epdf/10.1002/wnan.70004

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New Turn-Table Micro-CT Scanner for Perfusion Imaging

Our new turn-table micro-CT scanner offers high-resolution, low-dose dynamic perfusion imaging in mice. Allphin AJ, Nadkarni R, Clark DP, Gil CJ, Tomov M, Serpooshan V, Badea CT. Turn-table micro-CT scanner for dynamic perfusion imaging in mice: design, implementation, and evaluation. … Continue reading

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Congratulations to Hae Sol Moon!

Congratulations to  runner-up Hae Sol Moon of the Robert F. Wagner All-Conference Best Student Paper Award, sponsored by SPIE and the Medical Imaging Perception Society!   

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Understanding Alzheimer’s, brain aging, & the role of APOE2 allele

In our study, we adopted an integrative approach that combined behavioral assessments, brain imaging, and blood transcriptomics to focus on the transition from middle to old age in APOE2 mice, leading to the identification of critical brain sub-networks and regions … Continue reading

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Leveraging 3D Bioprinting & Photon-Counting Computed Tomography for Regenerative Medicine

An exciting publication on our collaborative research focusing on the innovative applications of 3D Bioprinting and Photon-Counting CT. Gil CJ, Evans CJ, Li L, Allphin AJ, Tomov ML, Jin L, Vargas M, Hwang B, Wang J, Putaturo V, Kabboul G, … Continue reading

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