Category Archives: Uncategorized

Predictive Alzheimer’s Risk

Congratulations to QIAL’s Dr. Alexandra Badea and Dr. Trong-Kha Truong on receiving the 2025 Medical Physics Fall Seed Grant Award for their project, “Predictive Modeling of Alzheimer’s Disease Risk Using Explainable AI and High-Resolution MRI.”

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Visiting Fulbright Scholar: Dr Kristina Bliznakova

Delighted to host Dr. Kristina Bliznakova, Fulbright Scholar, at Duke’s Quantitative Imaging & Analysis Lab. Looking forward to teaming up on photon-counting CT and virtual  imaging.

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Virtual Wistar Rats Enable Realistic PCCT Simulations

Our team developed anatomically variable digital Wistar rat phantoms for realistic preclinical imaging simulations, enabling PCCT studies & reducing animal use. Segars, H. E., Nadkarni, R., Badea, C. T., Badea, A., Chin, B., Johnson, G. A., Payne, J., Samei, E., … Continue reading

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Rapping Research

Our QIAL lab member Rohan Nadkarni brought the heat at the BME retreat—taking 2nd place in the rapid-fire challenge with original rap lyrics

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Hae Sol Moon Defends PhD on Alzheimer’s Modeling

Congratulations! Dr. Hae Sol Moon has successfully defended his PhD on “Integrative Modeling of Alzheimer’s Disease Risk”.

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Celebrating Dr. Alex Allphin’s PhD Defense!

Huge congratulations to Dr. Alex Allphin on a successful PhD defense! A key member of our QIAL lab, Alex’s work has pushed the boundaries of imaging science.

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Mapping Exercise-Induced Brain Changes in Alzheimer’s Disease

Voluntary & enforced exercise drive distinct brain changes in Alzheimer’s models.MRI reveals how emotion, memory, & motor circuits adapt—showing exercise’s neuroprotective power. Badea A, Mahzarnia A, Reddy D, et al. Neuroimaging biomarkers of neuroprotection: Impact of voluntary vs. enforced exercise … Continue reading

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APOE-Dependent Cardiac Response to Exercise in Mice via PCCT

This study investigates the impact of exercise on cardiac function across different APOE genotypes in mice using low-dose cardiac photon-counting micro-CT and deep learning-based segmentation. Results show significant, genotype-dependent improvements in cardiac performance, with the largest effects observed in APOE3 … Continue reading

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QIAL Contributions to SPIE Medical Imaging 2025

Advancing Preclinical and AI-Driven Imaging  with our Work presented at SPIE Medical Imaging 2025: Deve​lopment of a virtual photon-counting micro-CT imaging platform for preclinical cancer studiesNadkarni R, Clark D, Allphin A, Qi Y, Mowery Y, Segars W, Badea CT.Presented on … Continue reading

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Nanoparticle Contrast Agents for Photon-Counting Computed Tomography

Our  review article is published:Devkota L, Bhavane R, Badea CT, Tanifum EA, Annapragada AV, Ghaghada KB. Nanoparticle Contrast Agents for Photon-Counting Computed Tomography: Recent Developments and Future Opportunities. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2025 Jan-Feb;17(1):e70004. doi: 10.1002/wnan.70004. PMID: 39948059. https://wires.onlinelibrary.wiley.com/doi/epdf/10.1002/wnan.70004

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