Category Archives: Uncategorized

Deep learning for lung nodule detection in micro-CT imaging

Detection of Lung Nodules in Micro-CT Imaging Using Deep Learning Matthew D. Holbrook; Darin P. Clark; Rutulkumar Patel; Yi Qi; Alex M. Bassil; Yvonne M. Mowery; Cristian T. Badea Tomography 2021, Volume 7, Issue 3, 358-372

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Advances in micro-CT imaging of small animals

Our  new review paper on Micro-CT is now published : D.P.Clark, C.T.Badea, Advances in micro-CT imaging of small animals”: Physica Medica, Volume 88, August 2021, Pages 175-192 

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Congratulations Dr. Matt Holbrook!

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Deep-learning based extension of dual-energy FoV

New deep learning paper on Clinical CT  from our group:  Evaluating renal lesions using deep-learning based extension of dual-energy FoV in dual-source CT—A retrospective pilot study.  Eur J Radiol. 2021 Jun;139:109734. doi: 10.1016/j.ejrad.2021.109734. Epub 2021 The code is available at: … Continue reading

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SPIE Medical Imaging 2021

Our QIAL papers presented at the SPIE Medical Imaging 2021: Clark DP, Badea CT. A constrained Bregman framework for unsupervised convolutional denoising of multi-channel x-ray CT data. SPIE Medical Imaging. 2021; 115950J. https://doi.org/10.1117/12.2581832  Holbrook MD, Clark DP, Badea CT. Deep … Continue reading

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Deep Learning Approaches for Spectral CT

Our keynote talk on Deep Learning Approaches in Spectral CT at the 2nd Annual Translational Imaging Conference AI and Machine Learning in Imaging.  

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Microcephaly with altered cortical layering in GIT1 deficiency revealed by quantitative neuroimaging

We combined MRI and micro-CT to show that lack of GIT1 results in skull shape abnormalities, brain atrophy, white matter and cortical layer deficiencies. Clustering of volume covariance adjacency matrices identified vulnerable brain networks. https://www.sciencedirect.com/science/article/pii/S0730725X20304537    

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Optimizing Diffusion Imaging Protocols for Structural Connectomics in Mouse Models of Neurological Conditions

Network approaches provide sensitive biomarkers for neurological conditions, such as Alzheimer’s disease (AD). Mouse models can help advance our understanding of underlying pathologies, by dissecting vulnerable circuits. In this work, we have examined the balance between spatial and angular resolutions … Continue reading

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Dual source hybrid spectral micro-CT using an energy-integrating and a photon-counting detector

Preclinical micro-CT provides a hotbed in which to develop new imaging technologies, including spectral CT using photon counting detector (PCD) technology. Spectral imaging using PCDs promises to expand x-ray CT as a functional imaging modality, capable of molecular imaging, while maintaining … Continue reading

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Deep learning based spectral extrapolation for dual‐source, dual‐energy x‐ray computed tomography

Data completion is needed in dual‐source, dual‐energy computed tomography (CT) when physical or hardware constraints limit the field of view (FoV) covered by one of two imaging chains. Here we published a new Deep Learning approach for Spectral Extrapolation!

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