GeMS Scientists Map Sex Chromosome Evolution in Fungi

In a study appearing early online Aug. 11 in PLOS Biology, Duke researchers have mapped the evolutionary turning point that transformed the pathogenic form of Cryptococcus from an organism of many sexes to one with only two. They found that during evolution, a reshuffling of DNA known as translocation brought together separate chunks of sex-determining genes onto a single chromosome, essentially mimicking the human X or Y chromosome. Joe Heitman, MD, PhD, is interviewed in the article. See the full article here at Duke Today.