Active funding announcements:
Duke Microbiome Center Rolling Voucher Program
Duke University has established shared resources that avail state-of-the-art technologies to interrogate microbiome structure and function to Duke investigators. The Duke Microbiome Center offers a rolling voucher program to provide its investigators access to these shared resources, particularly for microbiome projects that are not yet externally funded. Eligibility is limited to Duke Microbiome Center faculty and their trainees, and the maximum budget for each DMC faculty member is up to $10,000 within any two-year period. There is no deadline for these proposals. For more information, see the program announcement.
Duke Cancer Institute / Duke Microbiome Center Joint Partnership Pilot Award
The Duke Cancer Institute (DCI) and Duke Microbiome Center (DMC) are collaborating to award one development grant at the intersection of cancer and the microbiome. All requirements for this award are identical to the DCI’s Translational and/or Collaborative Research 2022 Spring Pilot RFA with the additional requirements that (a) the PI or one of the co-PIs must also be a member of the DMC, (b) the project must support interdisciplinary and collaborative research projects in cancer and the microbiome sciences at Duke University, and (c) the research strategy document must state “DCI/DMC collaborative award” after the title (see submission guidelines in the program announcement). Note that these proposals will be considered for both traditional DCI pilot funding as well as DCI/DMC funding, but will only be eligible for one funding award. This award is being advertised through both the DCI and DMC and the review committee will include members of both the DCI and DMC. For more information, see the webpage and program announcement. The deadline for proposals to this RFA is Monday, 14 March 2022.
Duke Microbiome Center Development Grants
The Duke Microbiome Center (DMC) supports microbiome science at Duke University through pilot project funding. The DMC is pleased to announce this new request for proposals for DMC Development Grants. The objective of the DMC Development Grant program is to support interdisciplinary and collaborative research projects in the microbiome sciences at Duke University. For more information, see the program announcement. The deadline for proposals to this RFA is 30 April 2022.
- 2021 Awardees:
- “Bariatric Surgery- and GLP-1-Induced Microbiome Changes in Asthma and Obesity“, Jennifer Ingram, PhD (Medicine); Claudia Gunsch, PhD (Co-Investigator – Civil & Environmental Engineering)
- “Nasopharynx-on-a-Chip: An Innovative Model to Study the Pediatric Respiratory Microbiome“, Matthew Kelly, MD MPH (Pediatrics); Shyni Varghese, PhD (Co-Investigator – Biomedical Engineering)
- “Gut Microbial Contributions to Fallback-Food Ecology: Lemurs as a Test Case“, Anne Yoder, PhD (Biology); Lawrence David (Co-Investigator – Molecular Genetics & Microbiology)
- 2020 Awardees:
Previous funding announcements:
Duke CFAR / Duke Microbiome Center Joint Partnership Pilot Award
The purpose of this funding opportunity is to support research aimed at elucidating the interplay between the microbiome and immune responses relevant to HIV-1, AIDS, or AIDS-related opportunistic infections and malignancies. The funding opportunity is a joint partnership between the Duke University Center for AIDS Research (CFAR) and the Duke Microbiome Center (DMC) and is intended to foster new inter-center collaborations. For more information, see the program announcement. This funding announcement is currently closed.
- 2021 Awardee:
- “Determining the Role of the Gut Microbiota in HIV Acquisition”, Neil Surana, MD PhD (Pediatrics)
Duke Microbiome Center COVID-19 Development Grant
The Duke Microbiome Center (DMC) supports microbiome science at Duke University through pilot project funding. The DMC is pleased to announce an urgent new request for proposals for DMC COVID-19 Development Grants. The objective of the DMC Development Grant program is to support research projects that address the microbiome and COVID-19. For more information, see the program announcement. This funding announcement is currently closed.
- 2020 Awardees:
- “Probiotics To Eliminate COVID-19 Transmission in Exposed Household Contacts”, Anthony Sung, MD (Medicine) and Paul Wischmeyer, MD (Anesthesiology)
- “Impact of the Gut and Respiratory Microbiota on Susceptibility to SARS-CoV-2 in Children”, Matthew Kelly, MD MPH (Pediatrics)
Grants-In-Aid for Microbiome Science
Microbial communities (microbiomes) are known to contribute significantly to human health and disease, regulate global biogeochemistry, and harbor much of our planet’s genetic diversity. The goal of this RFP is to support Duke faculty who want to pursue microbiome research in the context of their broader research programs. This RFP is focused on discovery science and not intended to supplement ongoing funded microbiome research efforts. Priority will be given (1) to applications which are exploratory in nature and for which support is difficult or impossible to obtain; (2) to junior members of the faculty or staff who, by reason of their being earlier in their careers, find it difficult to obtain research support; and (3) to teams of investigators representing multiple scientific disciplines. All Duke University faculty and staff are eligible, and the maximum budget is $20,000. For more information, see the program announcement. This funding announcement is currently closed.
- 2018 Awardees:
- “Microbial recognition from gut to brain”, Diego Bohórquez, PhD (Medicine)
- “Extreme metabolism in primates: A comparative study of the gut microbiome and metabolome across active and hibernating lemurs”, Marina Blanco, PhD (Duke Lemur Center)
Grants-In-Aid for Microbiome Bioinformatic Analysis
In 2016 and 2017, the Center for the Genomics of Microbial Systems (GeMS) announced a request for proposals for Grants-In-Aid for Microbiome Bioinformatic Analysis. The primary goal of this RFP is to support Duke faculty who want to pursue microbiome research in the context of their broader research programs. The secondary goal of this RFP is to promote use of core facility services for microbiome bioinformatics available in the Duke Genomic Analysis and Bioinformatics Core Facility through a partnership between GeMS and the Duke Center for Genomic and Computational Biology. This RFP is focused on discovery science and not intended to supplement ongoing funded microbiome research efforts. Priority is given to applications which are exploratory in nature and for which support is difficult or impossible to obtain, and to junior members of the faculty or staff who, by reason of their being earlier in their careers, find it difficult to obtain research support. The awardees in 2016 and 2017 are listed below.
- 2017 Awardees:
- “Epithelial-associated and luminal microbiota linked to inflammatory bowel disease involving the small intestine”, Gianna Hammer, PhD (Immunology)
- “Impacts of exposures to semi-volatile organic compounds (SVOCs) in indoor environments on the gut microbiomes of toddlers”, Heather Stapleton, PhD (Nicholas School of the Environment)
- “Unraveling the intestinal microbiome’s impact on clinical responses to PD-1/PD-L1 inhibition in patients with genitourinary cancers”, Tian Zhang, MD and Andrew Armstrong, MD (Medicine – Division of Medical Oncology)
- 2016 Awardees:
- “In sickness and in health: Effects of lemur microbiomes on condition-dependent olfactory signals and other biomarkers of wellness”, Christine Drea, PhD (Evolutionary Anthropology)
- “Characterizing Antibiotic Resistance Genes in Oceans (CARGO)”, Claudia Gunsch, PhD (Civil and Environmental Engineering)
- “Examining the association between the intestinal microbiota, plasma biomarkers, and acute graft-versus-host disease in pediatric hematopoietic stem cell transplant recipients”, Matthew Kelly, MD MPH (Pediatric Infectious Diseases)
- “Impact of Enterococcal Domination on the Development of Enterococcal Bloodstream Infection in Patients with Hematologic Malignancy”, Julia Messina, MD MSc (Medicine), Nelson Chao MD (Medicine), Anthony Sung, MD (Medicine).
- “The Microbiome of Cutaneous Scar Formation”, Jennifer Powers, MD (Dermatology)
Collaborative pilot projects in the role of complex microbial communities in environmental and human health
In September 2013, the Center for the Genomics of Microbial Systems (GeMS), in conjunction with the Institute for Genome Sciences & Policy (IGSP) announced a call for proposals for high risk/high impact research in the area of the genomics of complex microbial systems. Priority was given to groups of two or more Duke University investigators who will jointly pursue new lines of research. The following five projects were selected for pilot funding:
- “The human microbiome, antigenome, and autoimmunity”, Patrick Seed, MD, PhD (Pediatrics)
- “Developing methods for genetic analysis in intractable commensal gut bacteria”, John Rawls, PhD (MGM), Timothy Reddy, PhD (Biostatistcs and Bioinformatics)
- “Microbes and mines: Community-wide genomic and transcriptomic responses to environmental contamination and implications for environmental health”, Emily Bernhardt, PhD (Biology), Rytas Vilgalys, PhD (Biology), Jennifer Wernergreen, PhD (Nicholas School of the Environment)
- “Single-parasite sequencing to identify sex determinants among mating populations of Plasmodium falciparum”, Jen-Tsan Ashley Chi, MD, PhD (MGM), Joseph Heitman, MD, PhD (MGM)
- “Measurement and manipulation of environmental oxygen and the human gut microbiome”, Lawrence David, PhD (MGM), Marc Deshusses, PhD (Civil and Environmental Engineering)
For additional federal and foundation funding opportunities please visit the Duke University Funding Opportunities website.