Our new study delves into Alzheimer’s disease, revealing molecular pathways tied to hallmark biomarkers & cognitive decline. Pathway analysis identified VEGF-RB as a common link, offering insights into disease mechanisms & potential treatment avenues.
Mahzarnia, Ali, Lutz, Michael W., and Badea, Alexandra. ‘A Continuous Extension of Gene Set Enrichment Analysis Using the Likelihood Ratio Test Statistics Identifies Vascular Endothelial Growth Factor as a Candidate Pathway for Alzheimer’s Disease via ITGA5’. 1 Jan. 2024 : 635 – 648. Journal of Alzheimer’s Disease, vol. 97, no. 2, pp. 635-648, 2024.DOI: 10.3233/JAD-230934