Please join us for the next Journal Club scheduled for October 24th, 2019 when the following articles will be presented.

Nicole Jawitz, MD will discuss the IBD article:
Ustekinumab as Induction and Maintenance Therapy for Ulcerative Colitis.
N Engl J Med. 2019 Sep 26;381(13):1201-1214. PDF.  PMID: 31553833.

Authors of this trial evaluated ustekinumab as 8-week induction therapy and 44-week maintenance therapy in patients with moderate-to-severe ulcerative colitis.

Zachary Spiritos, MD will discuss the Hepatology article:
Identifying optimal candidates for early TIPS among patients with cirrhosis and acute variceal bleeding: a multicentre observational study.
Gut 2019;68:1297–1310. PDF PMID:30415233

Authors performed this large, multicentre, observational study to assess the effects of early TIPS (compared with standard treatment) on the mortality, failure to control acute bleeding or rebleeding, new or worsening ascites and overt hepatic encephalopathy (OHE) among patients with cirrhosis and AVB who were stratified by current available risk stratification systems.

Jose Ruiz, MD will discuss the “Hot Topic” article:
Randomized Trial of Medical versus Surgical Treatment for Refractory Heartburn
N Engl J Med 2019; 381:1513-1523.  PDF PMID: 31618539

Authors performed a randomized trial of medical therapy vs surgical therapy for patients with PPI-refractory heartburn symptoms.