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GI Journal Club – April 22, 2021

Article 1:

Terlipressin plus Albumin for the Treatment of Type 1 Hepatorenal Syndrome

N Engl J Med 2021;384:818-28

DOI: 10.1056/NEJMoa2008290

Summary: The CONFIRM trial was performed to determine if administration of Terlipressin is more effective than placebo in improving renal function in patients with cirrhosis and HRS type 1.

Fellow Presenter: April Wall

 

Article 2:

Simple sugar and sugar-sweetened beverage intake during adolescence and risk of colorectal cancer precursors: Adolescent sugar intake and colorectal polyp

Gastroenterology. (2021). E-pub ahead of print

DOI: https://doi.org/10.1053/j.gastro.2021.03.028

Summary: The incidence of colorectal cancer (CRC) is rising among younger adults. Greater exposure to potential lifestyle risk factors (e.g., diet, obesity, physical inactivity), particularly during early life, have been hypothesized as potential reasons. This study prospectively investigated the association of adolescent simple sugar and sugar-sweetened beverage intake with CRC precursor risk.

Fellow Presenter: Nancy Yang


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