The Luftig lab

Research

The overarching goals of the Luftig Lab research program are to understand the molecular mechanisms that enable Epstein-Barr virus to establish latency, switch to the lytic cycle, and promote disease. We use cutting-edge, cross-disciplinary and highly collaborative approaches to characterize the temporal dynamics and single cell heterogeneity of EBV infection. With these strategies, we aim to discover fundamental molecular circuits underlying transcriptional control, viral manipulation of host signaling pathways, and metabolic regulation that collectively influence infected cell fate decisions. By understanding the nature of viral control of infected host cells, we are also well positioned to discover vulnerabilities in EBV-associated diseases and characterize new therapeutic interventions in cell-based and pre-clinical animal models.
Go to Single Cell Infection Biology

Single Cell Infection Biology

Go to Regulation of Cellular Metabolism

Regulation of Cellular Metabolism

Go to Interplay Between EBV and Pf malaria in eBL Pathogenesis

Interplay Between EBV and Pf malaria in eBL Pathogenesis

Go to spontaneous productive infection from B-cell latency with new ebv strains

spontaneous productive infection from B-cell latency with new ebv strains

Go to Therapeutic advances for ebv-associated diseases

Therapeutic advances for ebv-associated diseases

Go to Cellular factors regulating ebv infection in epithelial cells

Cellular factors regulating ebv infection in epithelial cells

Check Out Our Publications!

Our Lab

Our History, People, and Lab Fun!
Studying EBV Since 2007
  • We currently have 7 students!

  • We currently have 2 Post-Docs!

  • In addition to the PI, we currently have a Lab Manager, an Administrative Coordinator, and a Research Technician!

  • We currently have 4 undergrads!

lab updates

Our Lab Philosophy