After participating in this module, students should understand the following:
- The properties of a compound that make it oxidizable
- How oxygen participates in an oxidative reaction
- How a compound becomes reduced
- Why neurons with oxidizable neurotransmitters are most susceptible to damage
- How an oxygen radical is formed
- How oxygen radicals oxidize substrates such as proteins, lipids and DNA
- The role of enzymes in oxidative reactions
- How oxidation of cellular components produces toxicity
This module integrates information from the following areas: chemistry, neurobiology, cell biology, biochemistry
