What did I learn?

The following questions will help you review concepts presented in this module.

1. Think of a biological membranes as an oreo cookie. It is a lipid bilayer with 2 parts – the outer (or chocolate cookie part) is __________________ and the inner part (or the creamy part) is ____________________. (fill in the blanks)
   1. hydrophilic; hydrophilic
   2. lipophilic; hydrophilic
   3. hydrophilic; hydrophobic
   4. hydrophobic; amphoteric
2. Certain drugs cannot get into the brain very easily because of the presence of a “blood-brain barrier”.  Lipophilic drugs like cocaine penetrate this protective barrier rather quickly, but charged compounds cannot.  This is because the blood-brain barrier consists of:
   1. Tightly packed capillary epithelial cells
   2. Tightly packed capillary endothelial cells
   3. Mucosal cell membranes
   4. Very small sacs known as alveoli
3. Research into the fields of drug abuse, pharmacology, and psychology indicates that the period of time between the introduction of a drug into the body and its ability to produce euphoria or pleasure is important in the abuse potential of that drug.  A user is more likely to continue cocaine use after:
   1. Snorting the drug
   2. Ingesting the drug
   3. Smoking the crack form of the drug
4. Cocaine is a molecule composed of C, H, O, and N atoms.  In solution, the drug exists in two forms in an equilibrium: the free base and the acid salt; the pH of the environment determines the predominant form.  The route of administration of cocaine depends on whether it is in the free base or acid salt form.  The ionized or polar form (the salt) of cocaine can be administered into the body in which of the following manners?
   1. Snorted and smoked
   2. Snorted, injected, and smoked
   3. Injected and smoked
   4. Snorted and injected
5. Drugs can be introduced into the body on the venous side or the arterial side of the circulatory system.  Which side of the circulatory system does cocaine reach first, if it is snorted or smoked?
   1. arterial, venous
   2. arterial, arterial
   3. venous, arterial
   4. venous, venous

Now, check your answers here.