Publications

Clare’s Google Scholar Page

Preprints

Smith CM, Baker RE, Proulx MK, Mishra BB, Long JE, Park SW, Lee H-N, Kiritsy MC, Bellerose MM, Olive AJ, Murphy KC, Papavinasasundaram K, Boehm FJ, Reames CJ, Meade RK, Hampton BK, Linnertz CL, Shaw GD, Hock P, Bell TA, Ehrt S, Schnappinger D, Pardo-Manuel de Villena F, Ferris MT, Ioerger TR, Sassetti CM. “Host-pathogen genetic interactions underlie tuberculosis susceptibility in genetically diverse mice.” 2020; bioRxiv

Jinich A , Zaveri A, DeJesus MA, Flores-Bautista E, Smith CM, Sassetti CM, Rock JM, Ehrt S , Schnappinger D , Ioerger TR, Rhee K. “The Mycobacterium tuberculosis transposon sequencing database (MtbTnDB): a large-scale guide to genetic conditional essentiality.” 2021; bioRxiv; Test out the MtbTnDB here!

Yaron TM, Heaton BE, Levy TM, Johnson JL, Jordan TX, Cohen BM, Kerelsky A, Lin T-Y, Liberatore KM, Bulaon DK, Kastenhuber ER, Mercadante MN, Shobana-Ganesh K, He L, Schwartz RE, Chen S, Weinstein H, Elemento O, Piskounova E, Nilsson-Payant BE, Lee G, Trimarco JD, Burke KN, Hamele CE, Chaparian RR, Harding AT, Tata A, Zhu X, Tata PR, Smith CM, Possemato AP, Tkachev SL, Hornbeck PV, Beausoleil SA, Anand SK, Aguet F, Getz G, Davidson AD, Heesom K, Kavanagh-Williamson M, Matthews D, tenOever BR, Cantley LC, Blenis J, Heaton NS. “The FDA-approved drug Alectinib compromises SARS-CoV-2 nucleocapsid phosphorylation and inhibits viral infection in vitro.” 2020; bioRxiv

Olive AJ, Smith CM, Baer CE, Coers J, Sassetti CM. “Mycobacterium tuberculosis evasion of Guanylate Binding Protein-mediated host defense in mice requires the ESX1 secretion system.” 2020; bioRxiv

2020

Bourgeois JS, Smith CM, Ko DC. “These Are the Genes You’re Looking For: Finding Host Resistance Genes.” 2020; PDF

 

Sigmon JS., Blanchard MW, Baric RS, Bell TA, Brennan J, Brockmann GA, Burks AW, Calabrese JM, Caron KM, Cheney RE, Ciavatta D, Conlon F, Darr DB, Faber J, Franklin C, Gershon TR, Gralinski L, Gu B, Gaines CH, Hagan RS, Heimsath EG, Heise MT, Hock P, Ideraabdullah F, Jennette JC, Kafri T, Kashfeen A, Kulis M, Kumar V, Linnertz C, Livraghi-Butrico A, Lloyd KCK, Lutz C, Lynch RM, Magnuson T, Matsushima GK, McMullan R, Miller DR, Mohlke KL, Moy SS, Murphy CEY, Najarian M, O’Brien L, Palmer AA, Philpot BD, Randell SH, Reinholdt L, Ren Y, Rockwood S, Rogala AR, Saraswatula A, Sassetti CM, Schisler JC, Schoenrock SA, Shaw GD, Shorter JR, Smith CM, St Pierre CL, Tarantino LM, Threadgill DW, Valdar W, Vilen BJ, Wardwell K, Whitmire JK, Williams L, Zylka MJ, Ferris MT, McMillan L,Pardo-Manuel de Villena F. “Content and Performance of the MiniMUGA Genotyping Array: A New Tool to Improve Rigor and Reproducibility in Mouse Research.” 2020; PDF

Bellerose MM, Proulx MK, Smith CM, Baker RE, Ioerger TR, Sassetti CM. “Distinct Bacterial Pathways Influence the Efficacy of Antibiotics against Mycobacterium tuberculosis.” 2020; PDF

 

 

Lovewell RR, Baer CE, Mishra BB, Smith CM, Sassetti CM. “Granulocytes act as a niche for Mycobacterium tuberculosis growth.” 2020; PDF

 

2019

Smith CM*, Proulx MK*, Lai R*, Kiritsy MC, Bell TA, Hock P, Pardo-Manuel de Villena F, Ferris MT, Baker RE, Behar SM, Sassetti CM. “Functionally Overlapping Variants Control Tuberculosis Susceptibility in Collaborative Cross Mice.” 2019;  bioRxiv, PDF (*Denotes equal contributions)

 

Siddharth S, Zaveri A, Dejesus MA, Smith CM, Baker RE, Ehrt S, Schnappinger D, Sassetti CM, Ioerger TR. “Statistical analysis of variability in TnSeq data across conditions using zero-inflated negative binomial regression.” 2019; bioRxiv, PDF

 

Bellerose MM, Baek SH, Huang CC, Moss CE, Koh EI, Proulx MK, Smith CM, Baker RE, Lee JS, Eum S, Shin SJ, Cho SN, Murray M, Sassetti CM. “Common Variants in the Glycerol Kinase Gene Reduce Tuberculosis Drug Efficacy.” 2019; PDF

 

2018

Smith CM & Sassetti CM. “Modeling diversity: do homogenous lab strains limit discovery?” 2018; PDF

 

 

 

Olive AJ, Smith CM, Kiritsy M, Sassetti CM. “The Phagocyte Oxidase controls tolerance to Mycobacterium tuberculosis infection.” 2018; bioRxiv, PDF

 

 

2017

Mishra BB, Lovewell R, Olive AJ, Zhang G, Wang W, Smith CM, Phuah JY, Long JE, Dubuke M, Palace S, Goguen JD, Baker JE, Nambi S, Mishra R, Booty MG, Baer C, McCormick B, Chen X, Sassetti CM. “Nitric oxide prevents a pathogen-permissive granulocytic inflammation during tuberculosis.” 2017; PDF

 

 

DeJesus M, Nambi S, Smith CM, Baker RE, Sassetti CM, Loerger TR. “Statistical analysis of genetic interactions in TnSeq data.” 2017; PDF

 

2016

Smith CM, Proulx MK, Olive AJ, Laddy D, Mishra BB, Moss C, Gutierrez NM, Bellerose MM, Barreira-Silva P, Phuah JY, Baker RE, Behar SM, Kornfeld H, Evans TG, Beamer G, Sassetti CM. “Tuberculosis susceptibility and vaccine protection are independently controlled by host genotype.” 2016; PDF

 

Smith CM, Jerkovic T, Trong T, McCarthy J, Foote SJ, McMorran BJ. “Griseofulvin impairs intraerythrocytic growth of Plasmodium falciparum through ferrochelatase inhibition but lacks activity in an experimental human infectivity study.” 2016; PDF

Gonzales NM, Howell VM and Smith CM*. “29th International Mammalian Genome Conference meeting report.” 2016. PDF (*Corresponding author)

2015

Smith CM, Jerkovic A, Puy H, Winship I, Deybach JC, Gouya L, van Dooren G, Goodman CD, Sturm A, Manceau H, McFadden GI, David P, Mercereau-Puijalon O, Burgio G, McMorran BJ, Foote SJ. “Red cells from ferrochelatase-deficient erythropoietic protoporphyria patients are resistant to growth of malarial parasites.” 2015; PDF

 

Previous:

Brizuela M, Huang HM, Smith C, Burgio G, Foote SJ, McMorran BJ. “Treatment of Erythrocytes with the 2-Cys Peroxiredoxin Inhibitor, Conoidin A, Prevents the Growth of Plasmodium falciparum and Enhances Parasite Sensitivity to Chloroquine.” 2014; PDF


McMorran BJ, Wieczorski L, Drysdale K, Chan J, Huang H, Smith CM, Mitiku C, Beeson JB, Burgio G, Foote SJ. “Platelet Factor 4 and Duffy Antigen Required for Platelet Killing of Plasmodium falciparum.” 2012; PDF 

 

Longley R, Smith C, Fortin A, Berghout J, McMorran B, Burgio G, Foote S, Gros P. “Host resistance to malaria using mouse models to explore the host response.” 2011; PDF