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Cleavage-furrow formation without F-actin – new publication in PNAS

A new paper on cytokinesis in Chlamydomonas has been published in PNAS. https://doi.org/10.1073/pnas.1920337117 In this paper, we demonstrated that F-actin is enriched in the cleavege-furrow region of dividing Chlamydomonas cells by using Lifeact marker.  Interestingly, however, there is no myosin co-localizing with F-actin in the furrow, suggesting that no “actomyosin” structure is directly involved in …

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Onishi Lab is Opening in January 2020!

We will investigate the fundamental core mechanisms of cytokinesis and their evolution from the common ancestors, using Chlamydomonas in our lab, and with collaborators who use other systems.  Join us for this exciting expedition!!