New collaboration paper (Yaning Yuan): Alternative proteoforms and proteoform-dependent assemblies in humans and plants. in Mol Syst Biol

https://pubmed.ncbi.nlm.nih.gov/38918600/

See also: https://www.oeaw.ac.at/gmi/news-events/news-press/tracing-the-origin-of-truncated-protein-variants

Graduate Student Yaning Yuan took part in a collaboration with Claire McWhite (Princeton) and Silvia Ramundo (GMI Vienna) in the study that identified a large number of proteins showing alternative proteoforms. One of such proteins, fibrocystin/PKHD1 shows the same pattern of cleavage-dependent processing as in humans. Yaning is now studying the potential role of PKHD1 in cell division in both Chlamydomonas and humans. Stay tuned!