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Bioinorganic Chemistry in 3D!

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Thanks to generous funding from Research Corporation for Science Advancement, students got the fun opportunity to dive into biochemistry through project-based learning with 3D printing and molecular animation as the key features!

Students in CHEM 342 (Bioinorganic Chemistry and Material) learned fundamental concepts of inorganic and biological chemistry through a comprehensive project. Each student chose a bioinorganic system to study throughout the semester. Their task: apply fundamental inorganic and biological chemistry concepts to understand how their particular system works… then, teach their classmates and THE WORLD about their topic. Students wrote papers, created 3D print files, and printed their molecules. To top it off, each student created a molecular animation and educational video to teach the chemistry of their molecule. All of these materials will be soon be available YouTube and on LibreText (ChemWiki) so that others have access to these learning resources!

ProLab: Undergraduate Research in the Curriculum!

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The Department of Chemistry and Physics has broken new ground on campus by integrating undergraduate research fully into our Chemistry Majors’ curriculum! The new “Pro-Lab” course for juniors and seniors now involves authentic, open-ended research projects! We’ve just finished this semester’s first project after 8 weeks, and we’ve made exciting new discoveries about the human copper transporter!

Way to go Chem Bells! We are so impressed and proud of your hard work. Prepare to see your data, your analysis, and your excellent writing (and your names!) in a scientific journal article soon!

The Haas Lab was featured in the Council for Undergraduate Research Blog! Check it out here:  Cottrell Scholars – A new generation

Emma explores life as a Duke chemistry researcher!!

Saint Mary’s student, Emma Bridgman, spent ten weeks exploring life as a chemistry researcher at Duke Univeristy. Emma is working in the Franz lab with graduate student, Steven Conklin to understand the antibiotic properties of human Histatin peptides. She is studying how copper works with Histatin to kill fungus. When Emma returns to us in mid-August, she will continue her work with the Franz lab from afar, using the equipment at Saint Mary’s College.

Chemistry researchers know that having fun out of the lab is important too! Graduate student Steven Conklin, Saint Mary's Student Emma Bridgman, and Duke Chemistry Professor, Dr. Kathy Franz take a break from a Durham Bull's Baseball game to pose for a picture.
Duke researchers know that having fun out of the lab is important too! Duke graduate student Steven Conklin, Saint Mary’s Student Emma Bridgman, and Duke Chemistry Professor, Dr. Kathy Franz take a break from a Durham Bull’s Baseball game to pose for a picture.
Emma is ambushed for a photo while she is performing a titration experiment in the glove box.
Emma is ambushed for a photo while she is performing a titration experiment in the glove box.

A scientist abroad!

My summer lab-mates in the Bal Lab.
My super summer lab-mates in the Bal Lab at the Institute of Biochemistry and Biophysics, Polish Academy of Science, Warsaw, Poland.

Scientific research is all about hard-working people, working together to solve really important problems! We’ve engaged in a new collaboration with the Bal Lab at the Polish Academy of Sciences. Dr. Haas spent 8 weeks in Warsaw, Poland this summer on a mini research sabbatical! It was a wonderful experience and together we made some important discoveries about extracellular Cu coordination chemistry! Stay tuned and you will find out about our work in the literature soon!

Thank you Ewalina Stefaniak, Karolina Bossak, Ewa, Krzysztof Drabikowski, Marcin Grynberg, Wojtek Bal, Magda Sokołowska, Tomasz Frączyk (all pictured above),  Wojciech Wróblewski, Ola Sparavier, and Dawid Płonka for a wonderful Summer in Warsaw!

Distillation!

Virtuoso Distillery in South Bend, IN is serious about their separation science! These two columns are fractional distillation columns, just like the ones we use in the chemistry lab at Saint Mary’s College (except a tad bigger). When I arrived, Virtuoso was “rescuing” a bad batch of wine by isolating its ethanol to make vodka!

These two fractionating columns are made of my favorite element, Cu!
These two fractionating columns are made of my favorite element, Cu!

What is Imposter Syndrome?

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Image: David Whittaker. Source: http://www.sfu.ca/dean-gradstudies/events/impostersyndrome.html

This one is for the smart, brave women in CHEM 342 who shared their experiences as women in STEM today in a class discussion. One of the places we landed was a discussion about imposter syndrome.  What is it?  Why does it exist?  How do we overcome it?  Here are some good places to start in answering these questions:

(Aside: Check out this Facebook group!! https://www.facebook.com/ChemWomen/?fref=ts)

Wikipedia Article
Original Paper on Imposter Phenomenon in High Achieving Women
Imposter Phenomenon Defined by Dr. Pauline Rose Clancy
Huffington Post:Do you Suffer from Imposter Syndrome?
Seven Ways to Start Overcoming Imposter Syndrome

Welcome, Christina!

This was Christina’s first day in lab!  Christina comes to us from Marian High School in Mishawaka, IN.  She is interested in understanding the relationship between copper and human disorders, like Alzheimer’s Disease.

Her first mission: regenerate the Coy anaerobic atmosphere.  Mission Accomplished!

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Christina is a junior at Marian High School in Mishawaka, IN. She is using peptides to investigate the role of methionine in protecting Ctr1 against oxidative damage during copper transport.

A visit to science utopia: New England Biolabs!

Alumni, Erin Reinhart, is interning at NEB this summer before she is off to Dartmouth College for her doctoral studies in Chemistry.  I was invited to give a talk about our research and I got the opportunity to visit Erin and her research advisor, Lana Saleh.   WOW!  NEB is an amazing place with amazing people and cutting-edge science!   Its like Disneyland for scientists!

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The NEB building has received a LEED certification and a Sustainable Building Design Award. All waste from the building (except radioactive) is recycled, composted, or treated through an onsite solar green algae & root filtering system before returning to the water table.
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Erin and I pose with a statue of the NEB founder and owner, Donald Comb. From the stories I’ve heard, Dr. Comb is a mixture of Jesus, Elvis, and Einstein.

 

 

 

 

 

 

 

 


 

Cell Biology of Metals Gordon Conference

I traveled to Mount Snow, VT to present our data and hypothesis about the reductase-like behavior of the human cellular copper transporter, Ctr1, at the Gordon Research Conference on Cell Biology of Metal Ions.  It was a fun and invigorating conference with many wonderful people and great scientific discussions.  Thanks to Denis Thiele and Amy Palmer for putting on a great meeting!

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With Dennis Thiele, conference organizer and my former dissertation advisor.
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After the last poster session. It was an invigorating conference!

 

 

 

 

 

 

 

Learning bio-XAS from the best!

I went to the Stanford Synchrotron Radiation Lightsource (SSRL) with collaborator Jake Pushie in order to collect some very timely data for our latest publication!  We ran some samples and Jake taught me the nitty-gritty about X-ray absorption spectroscopy on dilute biological samples.  Thanks to Jake and his smart, fun labmates, Ashley and Susan, for a fun and productive trip!

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