August of 2017
- Kaleb Naegeli begins new exciting post-doc at the UNC Catalyst for Rare Diseases–a research group at the Eshelman School of Pharmacy dedicated to understanding the basic biology of rare genetic conditions that interfaces with patient organizations to develop novel therapies for woefully understudied diseases.
July of 2017
- Lara Linden successfully defends her Ph.D.! Spectacular student and work.
June of 2017
- Lara Linden’s paper (with Kacy Gordon and Qiuyi Chi), “Identification of regulators of germ stem cell enwrapment by its niche in C. elegans” is accepted by Developmental Biology-a groundbreaking paper starting a new field looking at stem cell enwrapment in C. elegans.
May of 2017
- Laura Kelley, Zheng Wang and Elliot Hagedorn paper, “Live-cell confocal microscopy and quantitative 4D image analysis of anchor cell invasion through the basement membrane in C. elegans” is accepted by Nat. Protocols. The culmination of many long hours spent in the dark microscope room. Well done!
April of 2017
- Dave is promoted to Full Professor of Biology. Many thanks to the current members and alumni of the Sherwood group. It has been a wonderful journey with many more adventures to come.
March of 2017
- A hearty congratulations
to Kaleb Naegeli for an amazing Ph.D. defense. Spectacular work and amazing seminar–the committee was blown away. Very proud of this young lad.
- Congratulations to Dan Costa, Aastha Garde, and Sara Payne for passing their preliminary exams! What a productive and spectacular month. Well done!
- Ranjay’s Primer “Basement Membranes” is Published in Current Biology. A beautiful summary of basement membranes.
January of 2017
- Undergraduate Youlie Li joins the lab. Working with Aastha and forming the dream team.
October of 2016
- Dan Keeley is awarded a prestigious fellowship to develop an internship program in the state of North Carolina pairing recent Ph.D.’s with state legislators!
October of 2016
- Dave is appointed one of the new co-directors of the Embryology Course at the MBL in Woods Hole. MA: Duke Today, Regeneration Next Announcement.
- Duke undergraduate Jay Zussman joins the lab for independent research.
- Shelly and Zheng’s paper “Boundary cells restrict dystroglycan trafficking to control basement membrane sliding during tissue remodeling” is published in eLife.
- Recent star Duke graduate Jonathan Jeger joins the lab at a technician to work on genome editing of genes encoding basement membrane proteins.
- Duke undergraduates Thomas Wang and Tanner Johnson join the lab for independent research.
- Dave Returns home from summer sabbatical.
- Aastha Garde, Dan Costa and Sara Payne join the group from the CMB program as graduate students. Very excited about what these three will discover.
- Dave starts his sabbatical in Paris, France at the Institute Curie Institute as Mayent- Rothschild Fellow, see: Institut Curie
- Kacy and Eric receive post-doctoral fellowships-the Ruth L. Kirschstein Institutional National Research Service Award and the American Cancer Society postdoctoral award.
- Meghan, Ranjay and Qiuyi’s paper “SPARC Promotes Cell Invasion In Vivo by Decreasing Type IV Collagen Levels in the Basement Membrane” is published in PLoS Genetics.
- Grace Lim receives an honorable mention at the 2016 Student Poster Competition at the AAAS Annual Meeting in Washington, DC, February 13-14 AAAS Student Meeting Winners
- The multi-talented Eric Hastie joins the lab as a post-doctoral scholar!
- Lauren and Matt’s paper is accepted at PLOS Genetics!
- Dave S receives the Mayent-Rothschild-Institut Curie Award to visit the Curie institute this coming summer.
- Matt starts his new position at CELLSCRIPT in Madison, WI.
- Lauren successfully defends her thesis!
- Kaleb is awarded a Fellowship from the Biology Department!
- Lauren starts her new position as a Clinical Pharmacology Associate/Project Manager at Nuventra in Research Triangle Park, NC
- Meghan starts her post-doc at UCSF in Ron Vale’s lab.
- Wei’s paper, “Rab-10-dependent transport is required for dendrite arborization” is accepted at PLOS Genetics.
- Dave’s commentary, “A Developmental Biologist Outside-the-Cell Thinking” is published at the Journal of Cell Biology
- Dave speaks at the MMP Gordon Research Conference in Sunday River, Maine. https://www.grc.org/programs.aspx?id=12358
- Dave presents at “Imaging the Cell Meeting” in Bordeaux, France http://www.imagingthecell2015.com
- Meghan successfully defends her thesis!
- Meghan’s review article, “An active role for basement membrane modification and assembly in tissue sculpting” is published in the Journal of Cell Science. pubmed
- Kacy Gordon, a new post-doctoral fellow joins the lab. Kacy was a graduate student at the University of Chicago in Professor Ilya Ruvinsky’s lab, where she studied the evolution of transcriptional regulation.
- Grace Lim, Troy Huffman-Devey and Catherine Blebea were all award URS independent study grants for their work in the lab!
- Matt Clay was awarded a Damon Runyon postdoctoral fellowship for his project entitled, “Understanding how extrinsic signals direct a Rho GTPase switch to control cell invasion in vivo”.
- Grace Lim was awarded a George Barthalmus Undergraduate Research Award.
- Meghan and Dan’s (with Shelly and Elliott and Qiuyi) paper “B-LINK: A Hemicentin, Plakin, and Integrin-Dependent Adhesion System that Links Tissues by Connecting Adjacent Basement Membranes” is published in Developmental Cell.
- Lauren’s collaborative work with the Nance lab on a new targeted protein degradation system that can remove tagged proteins rapidly within individual cells is accepted in Development. “Repurposing an endogenous degradation system for rapid and targeted depletion of C. elegans proteins” Armenti, S.T., Lohmer, L.L, Sherwood, D.R., and Nance, J” pubmed
- The Sherwood lab has been certified as a Gold Level Green Lab (https://sites.duke.edu/greenlabs/). Thank you Qiuyi for making this possible.
- Zheng’s paper, “UNC-6 (netrin) stabilizes oscillatory clustering of the UNC-40 (DCC) receptor to orient polarity” is published in the Journal of Cell Biology and is featured on the cover. pubmed
- Dave plays for the Duke faculty team against the senior undergraduates (coached by Grant Hill).
- A lab gathering/reunion at the SDB meeting in Seattle
- Lauren Lilley is a best poster finalist at SDB meeting.
- Adam Schindler is awarded a talk in the Hilde Mangold Postdoctoral Symposium at the SDB meeting.
- Matt Clay was awarded a Duke Cancer Biology Training Grant Postdoctoral Fellowship.
- David Matus’ paper, “Cell division and targeted cell cycle arrest opens and stabilizes basement membrane gaps.” is published in Nature Communications. pubmed
- Adam Schindler’s paper “Identification of late larval stage developmental checkpoints in Caenorhabditis elegans regulated by Insulin/IGF and steroid hormone signaling pathways.” is published in PLoS Genetics. pubmed
- Benjamin Lacroix from Amy Maddox’s lab publishes an in vivo imaging story of tubulin with help from Shinji in our group in Developmental Cell. “In situ imaging in C. elegans reveals developmental regulation of microtubule dynamics.” pubmed
- Zheng’s paper, ” MIG-10 (lamellipodin) has netrin-independent functions and is a FOS-1A transcriptional target during anchor cell invasion in C. elegans” is published in Development. pubmed
- Laura and Elliott’s paper, “ADF/cofilin promotes invadopodial membrane recycling during cell invasion in vivo” is published in the Journal of Cell Biology. pubmed
- Lauren’s paper, “Invadopodia and basement membrane invasion in vivo” is published in Cell Adhesion and Cell Migration. pubmed
- Laura Kelley’s review, “Traversing the basement membrane in vivo: a diversity of strategies” is published in the Journal of Cell Biology. pubmed
- Matt Clay, a new post-doctoral fellow, joins the lab. Matt was a graduate student at the University of Wisconsin in Madison studying neural crest cell migration in zebrafish in Professor Mary Halloran’s laboratory.
- Wei Zou begins new position as a post-doctoral fellow in Professor Kang Shen’s lab at Stanford University.
- David Matus begins new position as an Assistant Professor in the Biochemistry and Cell Biology Department at Stony Brook University.
- Zheng Wang begins new position as a Clinician and Researcher at Wuhan Union Hospital, China.