We are members of the NIH Co-Clinical Imaging Research Resources Program (CIRP). CIRP promotes development of quantitative imaging resources for therapeutic or prevention co-clinical trials that study both patients and human-in-mouse models.

Our  project  entitled “The Duke Preclinical Research Resources for Quantitative Imaging Biomarkers,”  focuses on optimizing preclinical MRI of the extremity and respiratory-gated CT of the lungs for utilization in a co-clinical trial evaluating radiation therapy and immunotherapy with a PD-1 inhibitor in a genetically engineered mouse model (GEMM) of soft tissue sarcoma. We make available:

• Protocols
• Code
• Data