Welcome to the Chen Lab

The Chen Lab is interested in understanding the molecular and genetic events underlying cancer progression and metastasis. The focus of our work is a series of genetically engineered mouse models that faithfully recapitulate human disease. Using a combination of mouse genetics, omics technologies, cross-species analyses and in vitro approaches, we aim to identify cancer cell–intrinsic and –extrinsic mechanisms driving aggressive and metastatic disease, with a long–term goal of developing new therapeutic strategies for preventing and treating human cancer. Read more


Recent News

The Chen Lab Receives the DoD PCRP Idea Development Award

Prostate Cancer Metastasis – Fueled by Fat? — NEJM

High-Fat Diet May Fuel Spread of Prostate Cancer — NYTimes

Genetics of Lipid Metabolism in Prostate Cancer — Nature Genetics

More news


Join Us!

We are actively seeking highly-motivated graduate students, postdoctoral fellows, and undergraduate students to join the team. Contact us if you are interested.


Research in the Chen lab is generously supported by: