The Holley Lab at Duke studies the role of non-coding RNAs and RNA modifications in cardiovascular health and disease. We have recently shown that snoRNA-guided 2’-O-methylation can regulate mRNA transcript abundance and translation. We are now seeking a doctoral or post-doctoral fellow to determine how snoRNA-guided RNA modifications impact cardiac development and heart failure. Contact Dr. Holley if you are interested. This project has R01 funding through at least 2024 and is not subject to a hiring freeze.
- Graduate student: Enrollment in Duke Graduate School
- Post-doctoral fellow: PhD, MD, or doctoral equivalent.
- Experience in cellular and molecular biology.
- Interest in RNA biology and/or cardiovascular research.