A lot of things happened in lab over the last 18 months! Here are some of the highlights.
Lee, J, Harris, AN, Holley, CL, Mahadevan, J, Pyles, KD, Lavagnino, Z, Scherrer, DE, Fujiwara, H, Sidhu, R, Zhang, J, Huang, SC-C, Piston, DW, Remedi, MS, Urano, F, Ory, DS, and Schaffer, JE. “Rpl13a small nucleolar RNAs regulate systemic glucose metabolism.” The Journal of clinical investigation 126, no. 12 (December 2016): 4616-4625.
Gokhale, NS, McIntyre, ABR, McFadden, MJ, Roder, AE, Kennedy, EM, Gandara, JA, Hopcraft, SE, Quicke, KM, Vazquez, C, Willer, J, Ilkayeva, OR, Law, BA, Holley, CL, Garcia-Blanco, MA, Evans, MJ, Suthar, MS, Bradrick, SS, Mason, CE, and Horner, SM. “N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection.” Cell host & microbe 20, no. 5 (November 2016): 654-665.
McCommis, KS, Hodges, WT, Brunt, EM, Nalbantoglu, I, McDonald, WG, Holley, C, Fujiwara, H, Schaffer, JE, Colca, JR, and Finck, BN. “Targeting the mitochondrial pyruvate carrier attenuates fibrosis in a mouse model of nonalcoholic steatohepatitis.” Hepatology (Baltimore, Md.) 65, no. 5 (May 2017): 1543-1556.
Fry, NJ, Law, BA, Ilkayeva, OR, Holley, CL, and Mansfield, KD. “N6-methyladenosine is required for the hypoxic stabilization of specific mRNAs.” RNA (New York, N.Y.) 23, no. 9 (September 2017): 1444-1455.
New Grants and Awards
NIH R03 (PI: Holley) Role of snoRNAs in regulation of cardiac hypertrophy
NIH R01 (PI: Zennadi) Role of RBC Reactive Oxygen Species and Their Vicious Cycle in Sickle Vasculopathy
NIEHS R41 Sub-Award (PI: Agris) Mass Spectrometric Screening of the Effect of Chemical Toxicants on the Human Epitranscriptome during Stem Cell Differentiation
AHA Strategically Focused Heart Failure Research Network (PI: Felker): Duke Center for the Study of Heart Failure and Diabetes
Duke Heart Center Leadership Council Junior Faculty Development Award: Dr. Holley
NIH T32 Fellowship: Dr. Law
Posters and Presentations
2017 Gordon Research Conference: RNA Editing. Ventura, CA. (Dr. Law)
2017 Duke-Stanford Cardiovascular Research Symposium (Dr. Ho)
2017 Duke Molecular Genetics and Microbiology Departmental Retreat (Drs. Law and Ho)
2017 North Carolina Symposium on RNA Biology XII (Dr. Law, who was awarded the Illumina Prize for her poster!)
New lab member!
Lab manager: Xinhe Yin