Skip to content

Publications

Bryson V, Wang C, Zhou Z, Singh K, Volin NM, Yildirim E, Rosenberg P. The D84G mutation in STIM1 causes nuclear envelope dysfunction and myopathy in mice. J Clin Invest. 2024 Feb 1;. doi: 10.1172/JCI170317. [Epub ahead of print] PubMed PMID: 38300705.

Yang, T., Ou, J., and Yildirim, E. (2022). Xist exerts gene specific silencing during XCI maintenance and impacts lineage-specific cell differentiation and proliferation during hematopoiesis. Nature Communications. 13, 4464. doi: 10.1038/s41467-022-32273-5.

Cao, J., Verma, S.K., Jaworski, E., Mohan, S., Nagasawa, C.K., Rayavara, K., Sooter, A., Miller, S.N., Holcomb, R.J., Powell, M.J., Ji, P., Elrod, N.D., Yildirim, E., Wagner, E.J., Popov, V., Garg, N.J., Routh, A.L., Kuyumcu-Martinez, M.N. (2021) RBFOX2 is critical for maintaining alternative polyadenylation patterns and mitochondrial health in rat myoblasts. Cell Rep. 2021. 37(5):109910. doi: 10.1016/j.celrep.2021.109910.

Kadota, S., Ou, J., Shi, Y., Lee, J.T., Jiayu, S., and Yildirim, E. (2020). Nucleoporin 153 links nuclear pore complex to chromatin architecture by mediating CTCF and cohesin binding. 11, 2606. Nature Communications. doi.org/10.1038/s41467-020-16394

Yang, L., Yildirim, E., Kirby, J.E., Press, W. and Lee, J.T. (2020). Widespread organ tolerance to Xist loss and X reactivation except under chronic stress in the gut. Proc Natl Acad Sci USA. 117 (8): 4262-4272.

Sun, J., Shi, Y., and Yildirim, E. (2019). Nuclear pore complex in cell type-specific chromatin structure and gene regulation. Trends in Genetics.. 35(8):579-588. doi.org/10.1016/j.tig.2019.05.006

Yang, T., Shi, Y. and Yildirim, E. (2017). Implications of Long Noncoding RNAs in Cancer Epigenetics. In Cancer and Noncoding RNAs. Translational Epigenetics Series. 1, pp 381-406. (Chakrabarti, J. and Sanga, M. eds), Elsevier Academic Press.

Yang, T., and Yildirim, E. (2017) Epigenetic and LncRNA-mediated Regulation of X-chromosome Inactivation and Its Impact on Pathogenesis. Current Pathobiology Reports. 5 (1), 1-12 doi:10.1007/s40139-017-0120-3.

Savol, A.J., Wang, P.I., Jeon, Y., Cologneri, D., Yildirim, E., Pinter, S.F., Payer, B., Lee, J.T., and Sadreyev, R.I. (2017) Genome-wide identification of autosomal genes with allelic imbalance of chromatin state. PLoS One. 12, (8) e0182568. doi: 10.1371/journal.pone.0182568. eCollection 2017.

Pinter, S.F., Colognori, D., Beliveau, B.J., Sadreyev, R.I., Payer, B., Yildirim, E., Wu, C.T., and Lee, J.T. (2015) Allelic imbalance is a prevalent and tissue-specific feature of the mouse transcriptome. Genetics. 200 (2), 537-549.

O’Connell, K.E., Mikkola, A.M., Stepanek, A.M., Vernet, A., Hall, C.D., Sun, C.C., Yildirim, E., Staropoli, J.F., Lee, J.T., Brown, D.E. (2015) Practical murine hematopathology: a comparative review and implications for research. Comp Med. 65, 96-113.

Yildirim, E., Kirby, J.E., Brown, D.E., Mercier, F.E., Sadreyev, R.I., Scadden, D.T., and Lee, J.T. (2013). Xist RNA is a potent suppressor of hematologic cancer in mice. Cell. 152, 727-742.
Featured in: Seton-­Rogers, S. (2013). Non‐coding RNAs: The cancer X factor. Nat Rev Cancer. 13(4), 224-225.

Sadreyev, R.I., Yildirim, E., Pinter, S.F., and Lee, J.T. (2013). Bimodial quantitative relationships between histone modifications for X-linked and autosomal loci. Proc Natl Acad Sci USA. 110, 6949-6954.

Yildirim, E.*, Sadreyev, R.I.*, Pinter, S.F., and Lee, J.T. (2012). X-chromosome hyperactivation in mammals via nonlinear relationships between chromatin states and transcription. Nat Struct Mol Bio. 19(1), 56-61. *Equal contribution.
Featured in: Birchler, J.A. (2012). Claims and counterclaims of X-chromosome compensation. Nat Struct Mol Bio. 19(1), 3-5.

Pinter, S.F., Sadreyev, R.I., Yildirim, E., Jeon, Y., Ohsumi, T., Borowsky, M., and Lee, J.T.(2012). Spreading of X chromosome inactivation via a hierarchy of defined Polycomb stations. Genome Res. 10, 1864-76.

Yildirim, E.*, Carey, M.A.*, Card, J.W., Dietrich, A., Flake, G.P., Zhang, Y., Bradbury, J.A., Rebolloso, Y., Germolec, D.R., Morgan, D.L., Zeldin, D.C., and Birnbaumer, L. (2012). Severely blunted allergen-induced pulmonary Th2-cell response and lung hyperresponsiveness in Type 1 transient receptor potential channel (TRPC1)-deficient mice. Am J Physiol Lung Cell Mol Physiol. 303 (6), 539-49. *Equal contribution.

Liu, X., Cheng, K.T., Bandyopadhyay, B.C., Pani, B., Dietrich, A., Paria, B.C., Swaim, W.D., Beech, D., Yildirim E., Singh, B.B., Birnbaumer, L., and Ambudkar, I. (2007). Attenuation of store-operated Ca2+ current impairs salivary gland fluid secretion in TRPC1(-/-) mice. Proc Natl Acad Sci USA. 104, 17543-17547.

Yildirim, E.,and Birnbaumer, L. (2007). TRPC2: molecular biology and functional importance. In “Handbook of Experimental Pharmacology“. (Flockerzi, V. ed), (179): 53-75. Springer-Verlag Heidelberg Press.

Liao, Y., Erxleben, C., Yildirim, E., Abramowitz, J., Armstrong, J.L., and Birnbaumer, L. (2007). Orai proteins interact with TRPC channels and confer responsiveness to store depletion. Proc Natl Acad Sci USA. 104, 4682-4687.

Abramowitz, J., Yildirim, E., and Birnbaumer, L. (2006). The TRPC Family of Ion Channels: relation to the TRP superfamily and role in Receptor- and Store-operated Calcium Entry. In “The TRP Family of Ion Channels“. (Liedke, W., ed). CRC Press.

Birnbaumer, L., Yildirim, E., Liao, Y., and Abramowitz, J. (2006). Molecular and functional diversity of the TRP family of ion channels. TRPC channels and their role in ROCE/SOCE. In “Insights into receptor function and new drug development targets”, 5th IPSEN Colloquium in Medicine and Research Endocrinology. (Conn, P.M., Kordon, C., and Christen, Y., eds.). Sringer-Verlag Press, Heidelberg, pp1- 22.

Dietrich, A., Menderos y Schnitzer M., Gollasch, M, Gross, V., Storch, U., Dubrovska, G., Obst, M., Yildirim, E., Salanova, B., Kalwa, H., Essin, K., Pinkenburg, O., Luft, F.C., Gudermann, T., and Birnbaumer, L. (2005). Increased vascular smooth muscle contractility in TRPC6-/- mice. Mol Cell Bio. 25, 6980-6989.

Yildirim, E., Kawasaki, B.T., and Birnbaumer, L. (2005). Molecular cloning of TRPC3a, an N-terminally extended, store-operated variant of the human C3 transient receptor potential channel. Proc Natl Acad Sci USA. 102, 3307-3311.

Birnbaumer, L., Yildirim, E., and Abramowitz, J. (2003). A comparison of the genes coding for canonical TRP channels and their M, V, and P relatives. Cell Calcium. Special Issue: TRP channels: facts, fictions, challenges. 33 (5-6), 419-432.

Yildirim E., Dietrich, A., and Birnbaumer, L. (2003). The mouse C-type transient receptor potential 2 (TRPC2) channel: Alternative splicing and calmodulin binding to its N terminus. Proc Natl Acad Sci USA.100, 2220-2225.

Leave a Reply