Mechanisms underlying bacterial fitness in the intestine A central challenge in microbiome science is defining how individual bacterial species achieve ecological fitness in the gut and how strain-level variation shapes host physiology. Phocaeicola vulgatus (Pvu)…
Mechanisms of intestinal repair and inflammation The intestine must sustain barrier integrity and immune balance despite constant microbial and chemical stress; failure of these homeostatic mechanisms contributes to sepsis, inflammatory bowel disease, and related disorders.…
This article identifies intestinal enteroendocrine cell subtypes in zebrafish and provides the first systematic description of the peptide hormones they produce. Published in PLOS Biology.
This article reveals that the epithelial transcription factor Elf3 mediates host immune responses to microbiota and protects against aerocystitis in zebrafish. Published in mBio.
The Rawls lab is happy to welcome Dr. Laura Childers, a new postdoctoral fellow who recently received her Ph.D. in Dr. Michel Bagnat’s lab here at Duke University. Laura is supported by the Digestive Disease…
The Rawls lab bids a fond farewell to Lizzie Reich who has worked with our lab and the Duke Zebrafish Core Facility as a Research Technician for the past two years.
Congratulations and farewell to Briana Davis and Maggie Morash on their successful defenses of their Ph.D. dissertations! Bri is moving on to be a Medical Writer with AdMed in Philadelphia, and Maggie is returning to…
This review article summarizes recent insights from human and animal studies into early subclinical stages of the inflammatory bowel diseases. Published in Am J Physiol Gastrointest Liver Physiol.
