Surgical services focus on development and application of window chamber models to study functional biology and physiology in tumors and other disease or normal tissue sites. Surgical models for intravital microscopy exist for skin, liver, gut, cranium, lung, muscle. Two surgical suites are available, as well as an experienced surgeon for assistance or model development. We also have a Zeiss surgical stereo microscope. doi:10.1038/nprot.2011.349