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Integrating evolutionary dynamics into clinical cancer treatment

This conversation was led by Robert Gatenby, Co-Director of the Center of Excellence for Evolutionary Therapy and Chair of the Department of Diagnostic Imaging at the Moffitt Cancer Center. In the talk, Dr. Gatenby outlined basic evolutionary principles and mathematical models used to design clinical therapies with the goal of both control and cure of metastatic cancers. He summarized the results of the first evolution-based clinical trial in metastatic, castrate-resistant prostate cancer. After the talk, additional perspectives on how the research applies in a clinical setting was presented by Shelley Hwang, Mary and Deryl Hart Distinguished Professor of Surgery and Chief of Breast Surgery at Duke.

Robert Gatenby in a Zoom meeting Shelley Hwang in a Zoom meeting

Resources discussed:

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