REPRESENTATIVE PUBLICATIONS
2024
Toll, K., and J.H. Willis. 2024. The genetic basis of traits associated with the evolution of serpentine endemism in monkeyflowers. Evolution 78: 111-126.
2021
Coughlan, J. M., M. Wilson Brown and J. H. Willis. 2021. The genetic architecture and evolution of life-history divergence among perennials in the Mimulus guttatus species complex. Proceedings of the Royal Society B, in press.
2020
Coughlan, J. M., M. Wilson Brown and J. H. Willis. 2020. Patterns of Hybrid Seed Inviability in the Mimulus guttatus sp. Complex Reveal a Potential Role of Parental Conflict in Reproductive Isolation. Current Biology 30: 83-93.
Flores-Vergara, M., Oneal, E., et., al. 2020. Developmental Analysis of Mimulus Seed Transcriptomes Reveals Functional Gene Expression Clusters and Four Imprinted, Endosperm-Expressed Genes. Frontiers in Plant Science Volume 11.
2019
Coughlan, J. M. and J. H. Willis. 2019. Dissecting the role of a large chromosomal inversion in life history divergence throughout the Mimulus guttatus species complex. Molecular Ecology 28: 1343-1357.
Selby, J., and J. H. Willis. 2019. Major QTL controls adaptation to serpentine soils in Mimulus guttatus. Molecular Ecology, in press.
2018
Toll, K., and J. H. Willis. 2019. Hybrid inviability and differential submergence tolerance drive habitat segregation between two congeneric monkeyflowers. Ecology 99: 2776-2786.
Troth, A., J. R. Puzey, R. S. Kim, J. H. Willis, and J. K. Kelly. 2018. Selective trade-offs maintain alleles underpinning complex trait variation in plants. Science 361: 475-478.
Ferris, K. G., and J, H. Willis. 2018. Differential adaptation to a harsh granite outcrop habitat between sympatric Mimulus species. Evolution 72: 1225-1241.
Barnett, L. L., A. Troth, and J. H. Willis. 2018. Plastic breeding system response to day length in the California wildflower Mimulus douglasii. American Journal of Botany 105: 779-787.
2017
Aeschbacher, S., J. P. Selby, J. H. Willis, and G. Coop. 2017. Population-genomic inference of the strength and timing of selection against gene flow. Proceedings of the National Academy of Sciences of the United States of America 114: 7061-7066.
Greenham, K., P. Lou, J. R. Puzey, G. Kumar, C. Arnevik, H. Farid, J. H. Willis, and C. Robertson McClung. 2017. Geographic Variation of Plant Circadian Clock Function in Natural and Agricultural Settings. Journal of Biological Rhythms 32: 26-34. Abstract
Puzey, J. R., J. H. Willis, J. K. Kelly. 2017. Population structure and local selection yield high genomic variation in Mimulus guttatus. Molecular Ecology 26: 519-535. Abstract
2016
Ferris K.G., L. L. Barnett, B. K. Blackman, and J.H. Willis. 2016. The genetic architecture of local adaptation and reproductive isolation in sympatry within the Mimulus guttatus species complex. Molecular Ecology 26: 208-224. Abstract
Lee, Y. W., L. Fishman, J. K. Kelly, and J. H. Willis. 2016. Fitness Variation Is Generated by a Segregating Inversion in Yellow Monkeyflower (Mimulus guttatus). Genetics. 202: 1473-1484. Abstract
Oneal, E., J. H. Willis, and R. G. Franks. 2016. Disruption of endosperm development is a major cause of hybrid seed inviability between Mimulus guttatus and Mimulus nudatus. New Phytologist. 210: 1107-1120. Abstract
2015
Ferris, K. G., T. Rushton, A. B. Greenlee, K. Toll, B. K. Blackman, and J. H. Willis. 2015. Leaf shape evolution has a similar genetic architecture in three edaphic specialists within the Mimulus guttatus species complex. Annals of Botany. 116 (2): 213-223. Abstract
Friedman, J., A.D. Twyford, J.H. Willis, and B. K. Blackman. 2015. The extent and genetic basis of phenotypic divergence in life history traits in Mimulus guttatus. Molecular Ecology. 24: 111–122. Abstract
2014
Ferris, K. G., J. P. Sexton, and J. H. Willis. 2014. Speciation on a local geographic scale: the evolution of a rare rock outcrop specialist in Mimulus. Philosophical Transactions of the Royal Society B. 369:20140001. Abstract
Oneal E., D. B. Lowry, K. M. Wright, Z. Zhu, and J. H. Willis. 2014. Divergent population structure and climate associations of a chromosomal inversion polymorphism across the Mimulus guttatus species complex. Molecular Ecology. 23:2844-2860. Abstract
Modliszewski, J. L., and J. H. Willis. 2014. Near-Absent Levels of Segregational Variation Suggest Limited Opportunities for the Introduction of Genetic Variation via Homeologous Chromosome Pairing in Synthetic Neoallotetraploid Mimulus. G3. g3.113.008441. Full Text
Fishman, L., J. H. Willis, C. A. Wu and Y. W. Lee. 2014. Comparative linkage maps suggest that fission, not polyploidy, underlies near-doubling of chromosome number within monkeyflowers (Mimulus; Phrymaceae). Heredity. 112:562–568 Abstract
Flagel, L. E., J. H. Willis, and T. J. Vision. 2014. The standing pool of genomic structural variation in a natural population of Mimulus guttatus. Genome Biology and Evolution. (1):53-64. Full Text
2013
Hellsten, U., Wright, K. M., Jenkins, J., Shu, S., Yuan, Y., Wessler, S. R., Schmutz, J., Willis, J. H., and D. S. Rokhsar. 2013. Fine-scale variation in meiotic recombination in Mimulus inferred from population shotgun sequencing. Proceedings of the National Academy of Science, USA. 110:19478-19482. Full Text
Friedman, J., and J. H. Willis. 2013. Major QTLs for critical photoperiod and vernalization underlie extensive variation in flowering in the Mimulus guttatus species complex. New Phytologist. 199:571–583. Abstract
Wright, K. M., D. Lloyd, D. B. Lowry, M. R. Macnair, J. H. Willis. 2013. Indirect Evolution of Hybrid Lethality Due to Linkage with Selected Locus in Mimulus guttatus. PLoS Biology. 11(2):e1001497. Full Text
2012
Sweigart, A. L., and J. H. Willis. 2012. Molecular evolution and genetics of postzygotic reproductive isolation in plants. F1000 Biology Reports. 4:23. Full Text
Modliszewski, J. L., and J. H. Willis. 2012. Allotetraploid Mimulus sookensis are highly interfertile despite independent origins. Molecular Ecology. 21:5280-5298. Abstract
Mojica, J. P., Y. W. Lee, J. H. Willis, and J. K. Kelly. Spatially and temporally varying selection on intrapopulation quantitative trait loci for a life history trade-off in Mimulus guttatus. Molecular Ecology. 21:3718-3728. Abstract
Mower, J. P., A. L. Case, E. R. Floro, and J. H. Willis. 2012. Evidence against equimolarity of large repeat arrangements and a predominant master circle structure of the mitochondrial genome from a monkeyflower (Mimulus guttatus) lineage with cryptic CMS. Genome Biology and Evolution 4:670-686. Full Text
Benedict, B. G., J. L. Modliszewski, A. L. Sweigart, N. H. Martin, F. R. Ganders, and J. H. Willis. 2012. Mimulus sookensis (Phyrmaceae), a new allotetraploid species derived from Mimulus guttatus and Mimulus nasutus. Madrono. 59:29-43. Full Text
Lowry, D. B., C. C. Sheng, Z. Zhu, T. E. Juenger, B. Lahner, D. E. Salt, and J. H. Willis. 2012. Mapping of ionomic traits in Mimulus guttatus reveals Mo and Cd QTLs that colocalize with MOT1 homologues. PLoS ONE. 7:e30730. Full Text
Strasburg, J. L., N. A. Sherman, K. M. Wright, L. C. Moyle, J. H. Willis, and L. H. Rieseberg. 2012. What can patterns of differentiation across plant genomes tell us about adaptation and speciation? Philosophical Transactions of the Royal Society B. 367:364-373. Full Text
Moran, E. V., J. H. Willis, and J. S. Clark. 2012. Genetic evidence for hybridization in red oaks (Quercus sect. Lobatae, Fagaceae). American Journal of Botany. 99:92-100. Abstract
Lowry, D. B., C. C. Sheng, J. R. Lasky, and J. H. Willis. 2012. Five anthocyanin polymorphisms are associated with an R2R3-MYB cluster in Mimulus guttatus (Phrymaceae). American Journal of Botany. 99:82-91. Abstract
2011
Magwene, P. M., J. H. Willis, and J. K. Kelly. 2011. The statistics of bulk segregant analysis using next generation sequencing. PLoS Computational Biology. 7:e1002255. Full Text
Scoville, A. G., Y. W. Lee, J. H. Willis, and J. K. Kelly. 2011. Explaining the heritability of an ecologically significant trait in terms of individual quantitative trait loci. Biology Letters. 7:896-898. Abstract
Anderson, J. T., J. H. Willis, and T. Mitchell-Olds. 2011. Evolutionary genetics of plant adaptation. Trends in Genetics. 27:258-266. Abstract
Cooley, A. M., J. L. Modliszewski, M. L. Rommel, and J. H. Willis. 2011. Gene Duplication in Mimulus Underlies Parallel Floral Evolution via Independent trans-Regulatory Changes. Current Biology. 21: 700-704. Abstract
2010
Lowry, D. B., and J. H. Willis. 2010. A widespread chromosomal inversion polymorphism contributes to a major life-history transition, local adaptation, and reproductive isolation. PLoS Biology. 8: e1000500. Full Text
Martin, N. H., and J. H. Willis. 2010. Geographical variation in postzygotic isolation and its genetic basis within and between two Mimulus species. Philosophical Transactions of the Royal Society B. 365:3469-2478. Full Text
Hall, M. C., D. B. Lowry, and J. H. Willis. 2010. Is local adaptation in Mimulus guttatus caused by trade-offs at individual loci? Molecular Ecology. 19:2739-2753. Abstract
Wu, C. A., D. B. Lowry, L. I. Nutter, and J. H. Willis. 2010. Natural variation for drought response traits in the Mimulus guttatus species complex. Oecologia. 162:23-33. Abstract
2009
Charlesworth, D., and J. H. Willis. 2009. The genetics of inbreeding depression. Nature Reviews Genetics. 10:783-796. Abstract
Cooley, A. M., and J. H. Willis. 2009. Genetic divergence causes parallel evolution of flower color in Chilean Mimulus. New Phytologist. 183: 729-739. Abstract
Lowry, D. B., M. C. Hall, D. E. Salt, J. H. Willis. 2009. Genetic and physiological basis of adaptive salt tolerance divergence between coastal and inland Mimulus guttatus. New Phytologist. 183: 776-788. Abstract
Scoville, A., Y. W. Lee, J. H. Willis, and J. K. Kelly. 2009. Contribution of chromosomal polymorphisms to the G-matrix of Mimulus guttatus. New Phytologist. 183: 803-815. Abstract
2008
Lowry, D. B., R. C. Rockwood, and J. H. Willis. 2008. Ecological reproductive isolation of coast and inland races of Mimulus guttatus. Evolution. 62:2196-2214. Abstract
Lowry, D. B., J. L. Modliszewski, K. M. Wright, C. A. Wu, and J. H. Willis. 2008. The strength and genetic basis of reproductive isolating barriers in flowering plants. Philosophical Transactions of the Royal Society B. 363:3009-3021. Full Text
McDaniel, S.F., J. H. Willis, and A. J. Shaw. 2008. The genetic basis of developmental abnormalities in interpopulation hybrids of the moss Ceratodon purpureus. Genetics. 179:1425-1435. Full Text
Case, A. L., and J. H. Willis. 2008. Hybrid male sterility in Mimulus (Phrymaceae) is associated with a geographically restricted mitochondrial rearrangement. Evolution. 62: 1026-1039. Abstract
Sweigart, A. L., N. H. Martin, and J. H. Willis. 2008. Patterns of nucleotide variation and reproductive isolation between a Mimulus allotetraploid and its progenitor species. Molecular Ecology. 17:2089-2100. Abstract
Cooley, A. M., G. Carvallo, and J.H. Willis. 2008. Is Floral Diversification Associated with Pollinator Divergence? Flower Shape, Flower Colour and Pollinator Preference in Chilean Mimulus. Annals of Botany. 101: 641-650. Abstract
Fishman, L., and J. H. Willis. 2008. Pollen limitation and natural selection on floral characters in the yellow monkeyflower Mimulus guttatus. New Phytologist. 177:802-810. Full Text
Wu, C. A., D. B. Lowry, A. M. Cooley, K. M. Wright, Y.W. Lee, and J. H. Willis. 2008. Mimulus is an emerging model system for the integration of ecological and genomic studies. Heredity. 100:220-230. PDF
2007
Mitchell-Olds, T., J. H. Willis, and D. Goldstein. 2007. What evolutionary processes influence natural genetic variation for phenotypic traits? Nature Reviews Genetics. 8:845-856. Abstract
McDaniel, S.F., J. H. Willis, and A. J. Shaw. 2007. A linkage map reveals a complex basis for segregation distortion in an interpopulation cross in the moss Ceratodon purpureus. Genetics. 176:2489-2500. Abstract
Rieseberg, L. H., and J. H. Willis. 2007. Plant speciation. Science. 317:910-914. Abstract
Martin, N. H., and J. H. Willis. 2007. Ecological divergence associated with mating system causes nearly complete reproductive isolation between sympatric Mimulus species. Evolution. 61:68-82. Abstract
Sweigart, A. L., A. Mason, J. H. Willis. 2007. Natural variation for a hybrid incompatibility between two species of Mimulus. Evolution. 61:141-151. Abstract
2006
Hall, M. C., and J. H. Willis. 2006. Divergent selection on flowering time contributes to local adaptation in Mimulus guttatus populations. Evolution. 60:2466-2477.
Aagaard, J. E., J. H. Willis, and P. C. Phillips. 2006. Relaxed selection among duplicate floral regulatory genes in Lamiales. Journal of Molecular Evolution. 63:493-503.
Fishman, L. and J. H. Willis. 2006. A cytonuclear incompatibility causes anther sterility in Mimulus hybrids. Evolution. 60:1372-1381.
Sweigart, A. L., L. Fishman, and J. H. Willis. 2006. A simple genetic incompatibility causes hybrid male sterility in Mimulus. Genetics. 172:2465-2479.
Hall, M. C., C. Basten, and J. H. Willis. 2006. Pleiotropic quantitative trait loci contribute to population divergence in traits associated with life-history variation in Mimulus guttatus. Genetics. 172:1829-1844.
2005
Aagaard, J. E., R. G. Olmstead, J. H. Willis, and P. C. Phillips. 2005. Duplication of floral regulatory genes in the Lamiales. American Journal of Botany. 92:1284-1293.
Hall, M. C. and J. H. Willis. 2005. Transmission ratio distortion in intraspecific hybrids of Mimulus guttatus: Implications for genomic divergence. Genetics. 170:375-386.
Fishman, L. and J. H. Willis. 2005. A novel meiotic drive locus almost completely distorts segregation in Mimulus (monkeyflower) hybrids. Genetics. 169:347-353.
2000-2004
Sweigart, A. L. and J. H. Willis. 2003. Patterns of nucleotide diversity are affected by mating system and asymmetric introgression in two species of Mimulus. Evolution, 57:2490-2506.
Fishman, L. A. J. Kelly, J. H. Willis. 2002. Minor quantitative trait loci underlie floral traits associated with mating system divergence in Mimulus. Evolution. 56 (11): 2138-2155.
Kelly, JK; Willis, JH. 2002. A manipulative experiment to estimate biparental inbreeding in monkeyflowers. International Journal of Plant Sciences. 163:575-579.
Fishman, L., A. J. Kelly, E. Morgan, and J. H. Willis. 2001. A genetic map in the Mimulus guttatus species complex reveals transmission ratio distortion due to heterospecific interactions. Genetics.159:1701-1716.
Fishman, L. and J. H. Willis. 2001. Evidence for Dobzhansky-Muller incompatibilites contributing to the sterility of hybrids between Mimulus guttatus and M. nasutus. Evolution. 55:1932-1942.
Kelly, J. K., and J. H. Willis. 2001. Deleterious mutations and genetic variation for flower size in Mimulus guttatus. Evolution. 55:937-942.
Earlier Papers
Willis, J. H. 1999. Inbreeding load, average dominance, and the mutation rate for mildly deleterious alleles in Mimulus guttatus. Genetics. 153:1885-1898.
Willis, J. H. 1999. The role of genes of large effect on inbreeding depression in Mimulus guttatus. Evolution. 53:1678-1691.
Willis, J. H. 1999. The contribution of male sterility mutations to inbreeding depression in Mimulus guttatus. Heredity. 83:337-346.
Sweigart, A., K. Karoly, A. Jones, and J. H. Willis. 1999. The distribution of individual inbreeding coefficients and pairwise relatedness in a population of Mimulus guttatus. Heredity. 83:625-632.
Schultz, S. T., M. Lynch, and J. H. Willis. 1999. The genomic mutation rate for fitness in Arabidopsis thaliana. Proceedings of the National Academy of Science, USA. 96:11393-11398.
Lynch, M., J. Blanchard, D. Houle, T. Kibota, S. Schultz, L. Vassilieva, and J. H. Willis. 1999. Spontaneous deleterious mutation. Evolution, 53:645-663.
Kelly, A. J. and J. H. Willis. 1998. Polymorphic microsatellite loci in Mimulus guttatus and related species. Molecular Ecology. 7:769-774.
Willis, J. H. 1996. Measures of phenotypic selection are biased by partial inbreeding. Evolution. 50:1501-1511.
Schultz, S. T. and J. H. Willis. 1995. Individual variation in inbreeding depression: the roles of inbreeding history and mutation. Genetics. 141:1209-1223.
Gimelfarb, A. and J. H. Willis. 1994. Linearity vs. nonlinearity of offspring-parent regression: experimental study. Genetics. 138:343-352.
Willis, J. H. and H. A. Orr. 1993. Increased heritable variation following population bottlenecks: The role of dominance. Evolution. 47:949-957.
Willis, J. H. 1993. Effects of different levels of inbreeding on fitness components in Mimulus guttatus. Evolution. 47:864-876.
Willis, J. H. 1993. Partial self-fertilization and inbreeding depression in two populations of Mimulus guttatus. Heredity. 71:145-154.
Willis, J. H. 1992. Genetic analysis of inbreeding depression caused by chlorophyll-deficient lethals in Mimulus guttatus. Heredity. 69: 562-572.
Willis, J. H., J. A. Coyne, and M. Kirkpatrick. 1991. Can one predict the evolution of quantitative traits without genetics? Evolution. 45:441-444.
