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Effects of Cannabis on Sperm

The goals of the Cannabis-Induced Potential Heritability of Epigenetic Revisions in Sperm (CIPHERS) project were to determine if cannabis use in humans and THC exposure in a rat model would lead to alterations in DNA methylation in sperm. With expanding legalization of cannabis and cannabis products, it’s important to understand the biological consequences so that consumers – and prospective consumers – can make informed decisions about use of these products.

Read about our findings from CIPHERS:

Pregnancy: Vulnerability to the Environment

The Newborn Epigenetics STudy (NEST) is a racially and ethnically diverse pregnancy cohort comprised of over 2,000 mother-infant pairs who were recruited during pregnancy between 2005 and 2011 from obstetrics clinics in Durham, North Carolina. The major objectives of NEST are to improve understanding of how the in utero environment shapes health and developmental outcomes, and the role of epigenetic mechanisms in mediating these effects. Data and biospecimens were collected at enrollment, birth and during childhood, and we are continuing to follow NEST participants as they enter early adulthood.

Read about findings from NEST:

Epigenetics and Gynecologic Malignancies