Host-Pathogen Genetic Interactions | Tuberculosis | Diverse Host Immunity
Rachel presented this weeks edition of Mad Mouse Paper Classics by teaching us all the math from Will Valdar’s 2006 Genetics paper “Genetic and Environmental Effects on Complex Traits in Mice”. A beautiful paper accompanied by a side of caramel slice and lamingtons – delicious aussie goods baked by Erin and Rachel!
Smith lab and Duke MGM are so excited to welcome the 2020 class of doctoral recruits!
We hope to see many of you in the fall!
Rachel prepared a presentation on a mouse genetics classic: Lander & Botstein, 1989!
She had a great time exploring the mathematical underpinnings of QTL mapping.
Great way to kick off Smith Lab meetings!
Clare gave an excellent Tuesday Seminar for the University Program in Genetics & Genomics!
Her talk, entitled “Host-pathogen genetic interactions underlie susceptibility to tuberculosis”, was a great opportunity to discuss future projects and the underlying visions of Smith Lab at Duke!
Genetic variation in both the host and pathogen underlies outcome to infection. In the Smith Lab, we take systems genetics approaches that combine host and pathogen diversity to define the specific host-pathogen interactions that alter susceptibility to tuberculosis. By understanding how these interactions drive immunity, new host-pathogen paired therapeutics and vaccines can be rationally designed.
Clare and Rachel spent a week training in required protocols and procedures for safe work with TB in the Duke Regional Biocontainment Laboratory.
We are currently recruiting a research technician and a postdoctoral fellow to join the team.
If you are interested in working on host and pathogen genetics, with a sprinkle of immunology, please apply at the links below and feel free to contact Clare for more information:
https://careers.duke.edu/job/Durham-RESEARCH-TECHNICIAN-II-NC-27710/597465900/
https://careers.duke.edu/job/Durham-POSTDOCTORAL-ASSOCIATE-NC-27710/595875900/
Open for science! Well, nearly…. Clare arrived in Durham and is currently ordering stuff (all the pipettes) ready for rotation students in Jan.
