Ashley L. Lennox+, Mariah L. Hoye+,Ruiji Jiang, Bethany L. Johnson-Kerner, Lindsey Suit, Srivats Venkataramanan, Charles J. Sheehan, Fernando C. Alsina, Brieana Fregeau, Kimberly A. Aldinger, Ching Moey, Iryna Lobach, Alexandra Afenjar, Dusica Babovic-Vuksanovic, Stéphane Bézieau, Patrick R. Blackburn, Jens Bunt, Lydie Burglen, Philippe M. Campeau, Perrine Charles, Brian H.Y. Chung, Benjamin Cogné, Cynthia Curry, Maria Daniela D’Agostino, Nataliya Di Donato, Laurence Faivre, Delphine Héron, A. Micheil Innes, Bertrand Isidor, Boris Keren, Amy Kimball, Eric W. Klee, Paul Kuentz, Sébastien Küry, Dominique Martin-Coignard, Ghayda Mirzaa, Cyril Mignot, Noriko Miyake, Naomichi Matsumoto, Atsushi Fujita, Caroline Nava, Mathilde Nizon, Diana Rodriguez, Lot Snijders Blok, Christel Thauvin-Robinet, Julien Thevenon, Marie Vincent, Alban Ziegler, William Dobyns, Linda J. Richards, A. James Barkovich, Stephen N. Floor, Debra L. Silver*, and Elliott H. Sherr*. Pathogenic DDX3X mutations impair RNA metabolism and neurogenesis during fetal cortical development In press.2020.
+ co-first authors (both Silver lab members); * co-corresponding authors.
Alsina, F and Silver, DL, “Post-transcriptional and translational control of neurogenesis: roles for RNA binding proteins”, Section: Generation of Neuronal Diversity, in Comprehensive Developmental Neuroscience. Elsevier. Editors (John Rubenstein and Pasko Rakic). In press. 2020.
Sheehan, C, McMahon, JJ, Serdar, L, and Silver, DL. Dosage dependent requirements of Magoh for cortical interneuron generation and survival. Development Jan 13; 147(1) 2020. Featured in preview article AND in a People behind the Paper article (both in the same issue)
Silver, DL, Rakic, P, Grove, EA, Haydar, TF, Hensch, TK, Huttner, WB, Molnár, Z, Rubenstein, JL, Sestan, N, Stryker, MP, Sur, M, Tosches, MA, Walsh, CA. “Evolution and Ontogenetic Development of Cortical Structures” in The Neocortex, ed. W. Singer, T. J. Sejnowski and P. Rakic. Pp. 61-93. Strüngmann Forum Reports, vol. 27, J. R. Lupp, series editor. Cambridge, MA: MIT Press. 2019 . (http://www.esforum.de and https://mitpress.mit.edu/books/emergent-brain-dynamics)
Alsina, F and Silver, DL. “Damage control in the developing brain: tradeoffs and consequences,” Trends in Neurosciences, Invited Spotlight. 22. 2019.
Vitali I, Fièvre S, Telley L, Oberst P, Bariselli S, Frangeul L, Baumann N, McMahon JJ, Klingler E, Bocchi R, Kiss JZ, Bellone C, Silver DL, Jabaudon D. Progenitor Hyperpolarization Regulates the Sequential Generation of Neuronal Subtypes in the Developing Neocortex. Cell. Jul 19. 2018
Risher WC, Kim N, Koh S, Choi JE, Mitev P, Spence EF, Pilaz LJ, Wang D, Feng G, Silver DL, Soderling SH, Yin HH, Eroglu C. Thrombospondin receptor α2δ-1 promotes synaptogenesis and spinogenesis via postsynaptic Rac1.J Cell Biol. July 27. 2018
Mitchell C and Silver DL. Enhancing our brains: Genomic mechanisms underlying cortical evolution. Seminars Cell and Developmental Biology. Aug 31. 2017 Review
Lennox, AL, Mao, H, and Silver DL. RNA on the brain: emerging layers of post-transcriptional regulation in cerebral cortex development. WIRES-Developmental Biology. Aug 24. 2017 Review
Miller EE, Kobayashi GS, Musso CM, Allen M, Ishiy FA, de Caires Junior LC, Guimarães ES, Griesi-Oliveira K, Zechi-Ceide RM, Richieri-Costa A, Bertola DR, Passos-Bueno MR, Silver DL. EIF4A3 deficient human iPSCs and mouse models demonstrate neural crest defects that underlie Richieri-Costa-Pereira Syndrome. Human Molecular Genetics. Mar 2 2017
Pilaz LJ, Silver DL.Moving messages in the developing brain-emerging roles for mRNA transport and local translation in neural stem cells. FEBS Letters. Mar 17. 2017 Review
Hanqian Mao, Hannah E. Brown and Debra L. Silver. Mouse models of Casc3 reveal developmental functions distinct from other components of the exon junction complex. RNA. Online Oct 25. Print Jan. 2017
Louis-Jan Pilaz, Ashley Lennox, Jeremy Rouanet, and Debra L. Silver. Dynamic RNA transport and local translation in radial glial progenitors of the developing brain. Current Biology. Dec. 19. 2016. Featured in accompanying preview article in same issue RNA transport: From Head to toe in Radial glia cells.
Mladen Roko-Rasin and Debra Silver. The crossroads of RNA regulation and function in neurodevelopment. Int J Dev Neurosci. Dec;55:101. 2016. Review.
John J. McMahon, Emily E. Miller, and Debra L. Silver. The exon junction complex in neural development and neurodevelopmental disease. Int J Dev Neurosci. Apr 9. 2016 Review.
Hanqian Mao, John J. McMahon, Yi-Hsuan Tsai, Zefeng Wang, and Debra L. Silver. Haploinsufficiency for core exon junction complex components disrupts embryonic neurogenesis and causes p53-mediated microcephaly. PLoS Genetics. Sept 12. 2016.
Louis-Jan Pilaz, John J. McMahon, Emily E. Miller, Ashley L. Lennox, Aussie Suzuki, Edward Salmon, and Debra L. Silver. Prolonged mitosis of neural progenitors alters cell fate in the developing brain. Neuron, online January 6. 2016.
Singh SK, Stogsdill JA, Pulimood NS, Dingsdale H, Kim YH, Pilaz LJ, Kim IH, Manhaes AC, Rodrigues WS Jr, Pamukcu A, Enustun E, Ertuz Z, Scheiffele P, Soderling SH, Debra L Silver, Ji RR, Medina AE, Eroglu C. Astrocytes Assemble Thalamocortical Synapses by Bridging NRX1α and NL1 via Hevin. Cell. Jan 14. 2016
Debra L. Silver. Genomic divergence and brain evolution: How regulatory DNA influences development of the cerebral cortex. Bioessays, online December 7. 2015. PDF Review
Louis-Jan Pilaz and Debra L. Silver.Post-transcriptional regulation in corticogenesis: how RNA-binding proteins help build the brain. WIREs RNA, June 18. 2015. PDF. Review
Hanqian Mao, Louis-Jan Pilaz, John J McMahon, Christelle Golzio, Danwei Wu, Lei Shi, Nicholas Katsanis, and Debra L. Silver. Rbm8a haploinsufficiency disrupts embryonic cortical development resulting in Microcephaly. The Journal of Neuroscience, May 6, 2015; PDF. *Featured on Journal cover and News and Views in same issue.
J. Lomax Boyd, Stephanie L. Skove, Jeremy P. Rouanet, Louis-Jan Pilaz, Tristan Bepler, Raluca Gordan, Gregory A. Wray, and Debra L. Silver. Human-Chimpanzee Differences in a FZD8 Enhancer alter cell-cycle dynamics in the developing neocortex. Current Biology, March 16; 2015.PDF. *Featured in over 75 print and online forums including Science, Science Translational Medicine, Current Biology, National Geographic, NPR.
W Christopher Risher, Sagar Patel, Il Hwan Kim, Akiyoshi Uezu,Srishti Bhagat, Daniel K Wilton, Louis-Jan Pilaz, Jonnathan Singh Alvarado, Osman Y Calhan, Debra L Silver, Beth Stevens, Nicole Calakos, Scott H Soderling, Cagla Eroglu. Astrocytes refine cortical connectivity at dendritic spines. eLife Dec 2014
Louis-Jan Pilaz and Debra L. Silver Live imaging of mitosis in the developing mouse embryonic cortex. JoVE. June 4; 2014.
John J McMahon, Lei Shi, and Debra L. Silver Generation of a Magoh conditional allele in mice. Genesis. April 27; 2014.
Debra L. Silver*, Karen E Leeds, Hun-way W. Hwang, Emily E. Miller, and William J Pavan*. The EJC component Magoh regulates proliferation and expansion of neural crest-derived melanocytes. Developmental Biology. March 15; 375 (2): 172-181. 2013. *Featured on cover. *co-corresponding authors.
Debra L. Silver, Dawn Watkins-Chow, Karisa Schreck, Tarran Pierfelice, Denise M Larson, Anthony Burnetti, Hunjun Liaw, Kyungjae Myung, Chris A Walsh, Nicholas Gaiano, and William J Pavan. The exon junction complex component, Magoh, controls brain size by regulating neural stem cell division. Nature Neuroscience. May; 13(5)551-558 2010. *Featured in accompanying News and Views,Regulating Brain Size, Nature Neuroscience, May; 13(5)531. 2010.