How is the brain assembled and sculpted during embryonic development? Addressing this question has enormous implications for understanding neurodevelopmental disorders affecting brain size and function. Our lab investigates genetic and cellular mechanisms controlling cerebral cortex development, and contributing to neurodevelopmental pathologies and brain evolution. We study neural progenitors, essential cells which generate neurons and glia of the developing brain. Learn more about our research:
RNA regulation and microcephaly
RNA localization and local translation
Human Brain Development and Evolution
We use live imaging of brain slices and neural progenitors, mouse genetics, and functional genomics. Read about some of our work from our recent publications in Current Biology, Neuron, PLoS Genetics. Our research has been featured in several outlets including Science, the Simons Foundation, and in an interview with Debby on NPR!
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