Our research

How do our brains develop-from just a few cells in the embryo to a complex adult organ? We study this fascinating question, focusing on neurogenesis of the cerebral cortex, the process whereby neurons are generated from neural progenitors. Defective neurogenesis impacts the type and number of neurons in the brain, and can cause broad neurodevelopmental disorders such as microcephaly. We have two major research interests in the lab:


We apply multidisciplinary approaches including live imaging of brain slices and neural progenitors, mouse genetics, and functional genomics.

Recent News from our lab:

WE ARE HIRING Postdoctoral Fellows: 

Our lab is accepting applications from highly motivated, hard-working postdoctoral applicants. This application is for a funded position to study how ZIKA virus and RNA binding proteins impair brain development. Previous experience in relevant fields of developmental neurobiology, stem cells, or RNA biology is a huge plus.  Must have a strong record of productivity and publications.  Please apply directly to Debra Silver (debra.silver@duke.edu)


Follow us on Twitter @TheSilverLab

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