Gustavo M. Silva, PhD
Head of the laboratory - Jack H. Neely Associate Professor
Gustavo is a biologist, who obtained his undergraduate and PhD degrees from the University of Sao Paulo, and had his postdoctoral training in the Center for Genomics and Systems Biology at New York University. His research interests revolve around the role of protein ubiquitination in cell fate, aging, and neurodegeneration. Gustavo has been inducted to the Bass Society of Fellows for excellence in research and teaching and has received the Deans Award for Excellence in Mentoring.
Beyond science, Gustavo enjoys listening to music, playing/watching soccer/combat sports, cooking and trying new flavors, and reading sociology. He tries to do at least three of the items at a time.
contact: gustavo.silva[at]duke[dot]edu
Margaret (Meg) Atchison
Administrative Assistant
Meg (BA, Psychology, NC Wesleyan) has 16 years of experience in administrative positions at Duke in both the School of Medicine and University. She enjoys helping students and faculty at Duke to shine by taking care of the administrative work so that they can focus on the research!
When she is not working, she enjoys creating, gardening, fitness, and spending time with friends and family.
contact: margaret[dot]barker[at]duke[dot]edu
Blanche Cizubu
Research Scientist/ Lab Manager
Blanche obtained her bachelor’s degree in Biochemistry from the University of Minnesota Twin Cities. She is always exploring new interests but is currently working on the deubiquitinating enzyme Ubp2 and how it regulates translation during stress. She is considering obtaining her CCRP certification and transitioning into clinical research.
In her free time, Blanche enjoys reading, talking to her family, exploring new places, and watching her comfort TV shows.
contact: blanche.cizubu[at]duke[dot]edu
Géssica Cabral Barros, PhD
Postdoctoral fellow
Géssica received her bachelor’s in Biochemistry and her Master’s degree in Agricultural Microbiology from the Federal University of Viçosa. She obtained her PhD degree in Biological Chemistry from Federal University of Rio de Janeiro. Her current interest is to understand the role of ribosome ubiquitination in translation control under oxidative stress conditions.
Outside of the lab, Géssica enjoys going to the gym, watching movies and spending time with her family and friends.
contact: gessica.cabral.barros[at]duke[dot]edu
Tonie Farris, PhD
Postdoctoral fellow
Tonie received her bachelor’s degree in Biology from Tennessee State University. She obtained her PhD in Biomedical Sciences from Meharry Medical College. Her research interest are in understanding cellular and molecular mechanisms of developmental and age-related neurological diseases.
In her free time, Tonie enjoys spending time with family, spending time in nature, gardening, and listening to music.
contact: tonie.farris[at]duke[dot]edu
Clara dos Santos
Graduate Student
Clara received her bachelor's degree in Biology from the University of Sao Paulo, Brazil, and is pursuing her doctoral degree through the Program in Biology at Duke. She is interested in understanding the connection between enzymes responsible for ubiquitination and energetic metabolism in the context of oxidative stress.
Besides lab work, Clara enjoys cooking, hanging out with friends and exploring new cultures.
contact: clara.dossantos[at]duke[dot]edu
Austin Maduka, PhD
Collaborator (NIH F30 Predoctoral MD/PhD fellow)
Austin received his undergraduate degree in Biochemistry & Molecular Biology from the University of Maryland, Baltimore County, and defended his PhD in Genetics & Genomics in the lab in 2024. He remains at Duke to complete his MD degree, and will soon pursue research-intensive residency programs in internal medicine and cardiology. He studies localized ubiquitin dynamics during stress in mammalian cells, and is ultimately interested in mechanisms of environmental stress on cardiovascular disease progression.
In his free time, Austin enjoys cooking, gymming, discovering new music, and going to concerts.
contact: austin.maduka[at]duke[dot]edu
Jorge Mato Frontela
Undergraduate Student
Jorge Mato started his undergraduate studies at the University of Havana and transferred to Duke University to finish his bachelor's degree in Biology with a concentration in Biochemistry and minoring in Computational Biology and Bioinformatics. He is interested in emerging omics science like Proteomics and Metabolomics and how they can be used to get a deeper understanding of how cell regulate their processes as a whole.
In his free time, Jorge likes going social dancing in the Triangle salsa scene, rehearsing and performing with dance clubs on campus, travelling, and watching shows on Netflix and Hulu.
Alyssa Estrada
Undergraduate Student
Alyssa is a junior at Duke University, majoring in computer science and planning to pursue a career in medicine. With interests in both computer science and molecular biology, Alyssa takes an interdisciplinary approach to her research and is primarily focused on using computational methods to discover and understand translational regulation of cells. Alyssa’s goal as a future physician is to help technology shape the future of medicine by integrating it into her own practice.
In her free time, Alyssa enjoys attending concerts, traveling, reading, and hiking!
Contact: alyssa.estrada[at]duke[dot]edu
Neil Nimmagadda
Undergraduate Student
Neil is a rising junior at Duke University, pursuing a major in neuroscience and a minor in computational biology/bioinformatics on the pre-medical track. He is currently interested in elucidating the key protein players and pathways involved in the ubiquitin-dependent mitophagy pathway, focusing on how ubiquitin ligases and autophagy receptors coordinate the recognition and clearance of dysfunctional mitochondria.
In his free time, he enjoys weightlifting, listening to music, and traveling.
Zaila Avant-garde
Undergraduate Summer Student
Zaila is an incoming freshman at the University of Maryland, where she will be studying Cell Biology & Genetics. She is currently investigating UBE2A deficiency syndrome via yeast models. In her free time, Zaila loves cooking/baking, listening to music, and learning random scientific facts.
Yue Chen
Undergraduate Visiting Student
Yue is a rising junior undergraduate student at Wuhan University in China. Yue plans to pursue a career in the biomedical research in the future. Her current research interest focuses on the roles of the ubiquitin-proteasome system and its related interacting proteins in neural development. In Prof. Silva's lab, she is engaged in studying the pathogenic mechanisms of Nascimento syndrome.
In her free time, Yue enjoys traveling, watching movies, listening to music, and swimming.
Rachel Field
Undergraduate Student
Rachel is a senior at Duke University, majoring in biology and minoring in chemistry and political science. Rachel plans to attend graduate school and pursue a career in biomedical research. She is interested in understanding processes and pathways that direct development and how their malfunction contributes to neurological and developmental disorders. At the Silva lab, she explores this in the context of X-linked intellectual disability type Nascimento.
In her free time, she loves to hike, read, do yoga, garden, and watch/tent for Duke basketball games!
contact: rachel[dot]field[at]duke[dot]edu
Joy Buchi-Ahiabuike
Undergraduate Student
Joy is a senior at Duke University, majoring in biology and minoring in chemistry. Her interests in molecular & cellular biology include how signaling pathway dysfunction impacts both organismal health and disease. She plans to attend medical school and become a physician, centering the biopsychosocial model of health in her practice.
In her free time, Joy enjoys singing, reading/writing poetry, and photography.
Silas Pontes de Almeida
Visiting Scholar
Silas received his bachelor’s degree in biology from the State University of Campinas, Brazil, and is pursuing his master’s degree through the Program in Molecular and Morphofunctional Biology at the State University of Campinas. He is currently interested in how mutations in ubiquitin-related proteins can disrupt their structure and function, leading to the X-linked intellectual disability type Nascimento.
In his free time, Silas enjoys watching movies and series, listening to music, and spending time with his cat.
Alumni
Chia-Yu Chen
Biostatistician 2024
post lab - Postdoc (Caltech)
Lubhanshi Garg
Graduate Visiting scholar 2024-2025
Neru Fulbright Fellow
Shannon Dougherty
Graduate Student 2024
post lab - Teaching Instructor (Duke Bio)
Elizabeth Lynfatt
Undergraduate Student (Summer 2024)
Ömür Kayikçi, PhD
Lab Manager (2023-2024)
Sofia Guerrero
Undergraduate Student (2020-2024)
2023 Goldwater Scholar | PhD at Stanford Neuroscience
Dinachi Okonkwo
Undergrad (2021-2023)
2022 Duke Faculty Scholar
Wigdan Hissien
Undergrad (summer 2023)
Vanessa Simões, Msc
Lab Manager (2017-2022)
Associate Consultant at Mckinsey & Co
Natori Maske
Lab Technician (2021-2022)
Lana Harley
Lab Technician (2019-2021)
Nate Snyder, PhD
Postdoctoral fellow (2018-2021)
Max Bucklan
Undergraduate Student (2019-2021)
PhD student at Duke UPGG
Julia Marshall
Undergraduate Student (2018-2020)
Andrew Gorman, PhD
Postdoctoral fellow (2018-2019)
Brian Gregory, PhD
Postdoctoral fellow (2019)
M. Sapphire Bowen-Kauth
Summer Undergraduate Student (2019) - SROP
MD/PhD Student UNC CH
Valeria Santa Melendez
Summer Undergraduate Student (2018) -SROP
PhD student at Purdue