Program

Click here to download the Agenda and Abstract Book.

Thursday, October 17th, 2019
Great Hall of the Trent Semans Center, Duke University
12:00 – 1:00 PM Registration (Great Hall)
1:00 – 2:35 PM SESSION I: TRANSLATION FIDELITY
Chair: Amanda Hargrove, Duke University
1:00 PM Opening Remarks, Stacy Horner, Duke University
1:10 PM Keynote Lecture: Rachel Green, Johns Hopkins University
“Colliding Ribosomes as an integrator of Cytoplasmic Stress Responses”
1:50 PM Yu-Hua Lo, NIEHS
“Unraveling the mechanism of substrate processing by the AAA-ATPase Rix7”
2:05 PM Hani Zaher, Washington University
“RNA damage, the ribosome and quality control”
2:35 PM Break
3:00 – 5:00 PM SESSION II: RNA PROCESSING
Chair: Jimena Giudice, UNC Chapel Hill
3:00 PM Rui Zhao, University of Colorado
“A unified mechanism for intron definition, exon definition, and back-splicing”
3:30 PM Adam Black, UNC Chapel Hill
“Clathrin heavy chain splice forms differentially affect striated muscle
physiology”
3:45 PM Nicholas Conrad, University of Texas Southwestern
“Mechanisms regulating S-adenosylmethionine homeostasis through intron
detention”
4:15 PM Marcos Morgan, NIEHS
“Role of RNA uridylation in germ line differentiation”
4:45 PM Jianguo Huang, Duke University
“Long non-coding RNA NEAT1 promotes sarcoma metastasis by regulating RNA
splicing pathways”
5:00 – 6:30 PM POSTER SESSION
5:00 PM Even Numbered Posters
5:45 PM Odd Numbered Posters
6:30 – 9:00 PM SYMPOSIUM BANQUET
Friday, October 18th, 2019
Great Hall of the Trent Semans Center, Duke University
8:00 – 8:30 AM Breakfast (Great Hall)
8:30 – 10:15 AM SESSION III: RNA EPIGENETICS
Chair: Mauro Calabrese, UNC Chapel Hill
8:30 AM Kate Meyer, Duke University
“Detecting m6A and its role in gene expression”
9:00 AM Ke Zhang, Wake Forest University
“Lsd1 and Lsd2 lysine demethylases regulate one another and play parallel
roles with other histone modifying enzymes in Schizosaccharomyces pombe”
9:30 AM Christopher Holley, Duke University
“Modification of mRNA by snoRNA-guided 2’-O-methylation”
10:30-12:10 PM SESSION IV: RIBOSOMES
Chair: Robin Stanley, NIEHS
10:30 AM Keynote Lecture: Susan Baserga, Yale University
“The RNA polymerase II transcription factor, Paired Box 9 (PAX9), regulates ribosome biogenesis and craniofacial development.”
11:10 AM Gustavo Silva, Duke University
“Ribosome control by K63 ubiquitin during oxidative stress”
11:40 PM Christine Dunham, Emory University
“RNA-mediated mechanisms of translation control”
12:10 – 1:15 PM LUNCH
1:15 – 3:10 PM SESSION V: RNA STRUCTURE AND GENE EXPRESSION
Chair: Qi Zhang, UNC Chapel Hill
1:15 PM Ribometrix Keynote Lecture: Phillip Bevilacqua, Penn State University
“RNA structure-function relationships under in vivo and in vivo-like conditions:
Impacts on RNA catalysis, folding, and transcriptome-wide response to stress”
1:55 PM Joseph Rodriguez, NIEHS
“Environmental regulation of the estrogen response in single cells”
2:25 PM Eda Yildirim, Duke University
“Regulation of chromatin architecture and transcription by nucleoporin
proteins”
2:55 PM Angela Yu, Cornell/Northwestern University
“Computationally reconstructing cotranscriptional RNA folding pathways from
experimental data”
3:10 PM Break
3:30 – 5:00 PM SESSION VI: RNA PROTEIN INTERACTIONS
Chair: Traci Hall, NIEHS
3:30 PM Daniel Dominguez, UNC Chapel Hill
“Features of RNA binding motifs”
4:00 PM Anthony Mustoe, Baylor College of Medicine
“Visualizing RNA structural ensembles by single molecule chemical probing”
4:15 PM Hong Wang, NCSU
“Cohesin SA1 and SA2 are RNA binding proteins”
4:30 PM Awards Presentation
5:00 PM Meeting Adjourns