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Exploitation of antibiotic heteroresistance to kill pan-resistant bacteria

This conversation was led by Dr. David Weiss, Professor in the Department of Medicine at Emory University. David Weiss performed his graduate research on Toll-like Receptors with Dr. Arturo Zychlinsky at NYU. He then studied virulence mechanisms of Francisella with Drs. Denise Monack and Stanley Falkow at Stanford, before starting his own lab at Emory University in 2008. His current research is largely focused on understanding mechanisms of antibiotic resistance and developing novel therapeutic approaches to combat this crisis. A major area of interest is in elucidating the factors controlling heteroresistance, a phenomenon in which a minor subpopulation of cells can cause antibiotic treatment failure. He received a Burroughs Wellcome Fund Investigator in the Pathogenesis of Infectious Disease award and was named a Kavli Fellow of the National Academy of Sciences and a Fellow of the American Association for the Advancement of Science (AAAS).

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