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Biological Sciences Undergraduate Research Fellows Blog

Plasmodium protein kinases

By: Moreen Njoroge

Under the supervision of Amber Eubanks, a third-year graduate student and I have been studying the biochemistry of kinases in Plasmodium, the parasite that causes malaria. Malaria kills hundreds of thousands of people each year across the globe. The primary...
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Brain-Interfacing Electrodes

By: Raj Borra

State of the art technology including electronics that can interface with the brain has been incredibly useful in both understanding how the brain works and how neural diseases develop and occur. One of the biggest challenges today is to create electrodes that...
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BRET and I

By: Margo Orlen

Forty to fifty percent of therapeutic drugs today target a class of plasma membrane proteins called G-protein coupled receptors (GPCRs) (Beaulieu & Gainetdinov, 2011). The dopamine receptor is a type of GPCR that, when activated by dopamine, plays a role...
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Hoping for a Glowing Connection

By: Chad Munger

The Bohórquez Lab focuses on the connection between the gut and the brain, especially how the brain perceives what the gut feels. Team members have performed a neurotracing using a monosynaptic rabies virus. The modified rabies virus they used could...
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My Project

By: Murotiwamambo Mudziviri

A lab resembles a giant organism made up numerous systems – in this case it’s the scientists – working towards a common goal. My role in The Perfect Lab is one of the many small parts that contribute towards the...
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Week 3: Research Project

By: Griffin Haas

The Pickup lab studies poxviruses and their interactions with host cells, as well as their potential to be used as vectors in immunizations. Previous studies using a poxvirus known as Modified Vaccinia Ankara (MVA) were conducted to try and elicit...
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Differentiation of Ependymal Cells

By: Emre Kiziltug

Hello everyone! This week I wrote about the overall research project in Kuo Lab and describe my particular role in it. I hope you enjoy it! Ependymal cells located in the walls of brain ventricles play an important role in neurogenesis...
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Research Project: iPSCs Differentiation into vSMCs

By: Elizabeth Snyder-Mounts

My research project for this summer is to model the protocol as outlined in the publication Generation of vascular endothelial and smooth muscle cells from human pluripotent stem cells (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566857/) for differentiation of induced pluripotent stem cells (iPSCs) into vascular...
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Mutagenesis and Yeast

By: Demi Zhu

The Jinks-Robertson Lab at Duke investigates genome stability and mutagenesis using yeast. Saccharomyces cerevisiae is used as a model organism because yeast is easy to grow, and has a cell cycle similar to that of human cells which is also regulated...
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The Environment and Genetics of Germination

By: Melissa Horowitz

When discussing the development of any type of organism, the topics of both genetics and the environment are strongly considered, which has contributed to the debate known as “nature vs. nurture.” At the Donohue Lab, both heredity and the environment...
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Zebrafish Cardiac Development and Gene Expression

By: Susan Zheng

The Poss lab focuses on the concepts and mechanisms of regeneration in zebrafish. Zebrafish are a known animal model system for studying regeneration because of their remarkable ability to regenerate lost tissue after injury. Adult zebrafish are capable of regenerating...
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Understanding Enhancers and Gene Expression

By: Hannah Ahrendt

Glossary: Promoter: A short sequence of DNA located just before the transcription start site for a gene, which is responsible for initiating the transcription of a gene, generally by recruiting RNA polymerase, the molecule responsible for DNA transcription. Transcription factor:...
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