In the Volkan lab, we study the developmental processes and molecular mechanisms that establish the basic organizational and functional principles of the neuronal circuits in the brain. We investigate how the neuronal circuits assemble, functionally mature, and remodel with experience or evolutionary processes to regulate and modify behaviors. We apply molecular genetics, genomics, developmental and systems level approaches in the olfactory system of the genetically tractable Drosophila melanogaster.
Questions we are interested in:
What are the developmental and molecular mechanisms generating 50 different olfactory receptor neuron fates with unique sensory and wiring properties?
How do these mechanisms change with experience and evolutionary processes to modulate behaviors?