My research focuses on the development of advanced machine learning approaches, statistical methods, and efficient computational tools on a Big Data infrastructure for precision medicine:
- Developing Advanced Statistical Methods and Reliable Computational Tools to discover clinically actionable genetic variants and clinical/environmental factors for disease diagnosis and personalized treatment;
- Developing Advanced Machine Learning Approaches to Mine Large-Scale Scientific Articles to discover disease- and/or drug-gene associations and other relevance;
- Developing New Statistical Methodologies and Computational Tools to detect disease-associated genetic variants by genome-wide association studies (GWAS) and/or phenome-wide association studies (PheWAS);
- Creating a Big Data System to store, manipulate, and analyze diverse genomic data and comprehensive clinical data derived from electronic health records (EHRs).
