A top medical center requires a strong presence in regenerative science and medicine. The DRC takes over the functions of Regeneration Next Initiative (RNI), Duke’s successful program in regenerative science and medicine, active from 2015 to 2020. RNI created a formal community and collaborative environment, hosted large events, led recruits of 4 outstanding new faculty, and supported trainees through several mechanisms including full 2-year postdoctoral fellowships. DRC will build on the accomplishments of RNI to grow and support regenerative science and medicine along with its partnering Departments.