A number of core resources are available at Duke, such as the following state of the art platforms for generating epigenome-wide discovery or targeted validation data.
WHOLE DNA METHYLONE (Data Generation):
Illumina 450k
methylation profiling
Next Generation Sequence/
target enrichment
Duke Molecular Physiology Institute
Genome Sequencing Shared Resource
David H Murdock Research Institute
TARGETED DNA METHYLONE (Data Generation):
Illumina 96-1536 GoldenGate methylation profiling
Qiagen
pyrosequencing
Sequenon
MassARRAY
Bisulfite
sequencing
Duke Molecular Physiology Institute
Murphy Lab
David H Murdock Research Institute (DHMRI)
DNA Analysis Facility
Duke Molecular Physiology Institute