Our collaboration with the Coloff lab is now online in Cell Reports

In this paper, we show that the amino acid transporter ASCT2 (SLC1A5) is the primary importer of serine in cancer cells. While ASCT2 is well known as a glutamine transporter in cancer, Conger and team show that serine and glutamine compete for uptake through ASCT2. ASCT2-mediated serine uptake is essential for purine nucleotide biosynthesis and estrogen receptor α (ERα) promotes … Read More

The PCB department posted a news piece announcing the opening of the Chidley and Darnell labs this September

Drs. Alicia Darnell and Christopher Chidley have been appointed as tenure-track Assistant Professors in the Department of Pharmacology and Cancer Biology. They will open their labs in September 2024 and are recruiting graduate students, research technicians, and postdocs. In an email to the department, Dr. Lee Zou, Chair of the Department of Pharmacology and Cancer Biology, wrote, “We are excited … Read More