We are a Research Laboratory in the Department of Pharmacology and Cancer Biology. We investigate the role of transporter proteins in nutrient and metabolite import/export and their impact on cell state and response to chemotherapeutics. We mainly use unbiased genetic screening approaches in cell and animal models followed by an array of cell biology, biochemistry and analytical chemistry techniques to identify critical small molecule transporters across different environments, characterize their function, and explore how the tumor microenvironment impacts cancer metabolism. Our research aims to guide the development of metabolic strategies to suppress tumor growth, and aid precision medicine efforts by revealing determinants of drug sensitivity.
We are recruiting at many levels. Please reach out to christopher.chidley(@)duke.edu to discuss opportunities:
We host graduate students enrolled in Duke-affiliated programs. Please email to set up a meeting to discuss potential rotation projects. We offer diverse projects across the fields of cancer biology, pharmacology, and transporter biology. Projects are primarily hypotheses-driven questions, unbiased genetic screening, or method development.
Please reach out by email with (i) a cover letter discussing specifically why our lab would be a good fit for your scientific and career goals, (ii) your CV, (iii) the name and contact information of 3 references.
Please express your interest by email, and include a copy of your CV. We are interested in post-bac research technicians willing to spend 2 years in the lab.
We host graduate students enrolled in Duke-affiliated programs. Please email to set up a meeting to discuss potential rotation projects. We offer diverse projects across the fields of cancer biology, pharmacology, and transporter biology. Projects are primarily hypotheses-driven questions, unbiased genetic screening, or method development.
Please reach out by email with (i) a cover letter discussing specifically why our lab would be a good fit for your scientific and career goals, (ii) your CV, (iii) the name and contact information of 3 references.
Please express your interest by email, and include a copy of your CV. We are interested in post-bac research technicians willing to spend 2 years in the lab.
