When the Numbers Don’t Move: Understanding Ceiling Effects, Floor Effects, and Limited Score Spread in MSK Patient‑Reported Outcomes

By: Chad Cook PT, PhD, FAPTA Introduction: I recently responded to a very supportive post on Linked-In that discussed a study we published two years ago on patient reported experience measures [1]. In the observational research study, we found that nearly all of the 50,000 plus physical or occupational therapy patients scored a near perfect […]

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Why Individualized Treatment Effects Matter More Than Averages in Musculoskeletal Care

By: Chad Cook PT, PhD, FAPTA Introduction: Imagine being able to say: “Based on your profile, you’re likely to respond better to graded activity than manual therapy.” Or: “Patients like you tend to improve more with individual physiotherapy than group-based exercise.” This should be the future of MSK care. It isn’t yet. If you’ve spent […]

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Spinal Manipulation: Lack of Precision Doesn’t Mean Lack of Skill

By: Mark Shepherd, PT, DPT, DSc Spinal thrust manipulation has been used for centuries, with evidence supporting its inclusion in neck and low back guidelines.1,2 Yet, how it’s taught and applied varies widely across and within professions, sparking debate among educators, clinicians, and researchers.3,4 Nim et al.’s recent systematic review5 and JOSPT blog6 challenge us […]

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What is the Natural History of Low Back Pain? It Depends

By: Chad E Cook PT, PhD, FAPTA Definition: The natural history of a disease refers to the progression of a disease in an individual over time, from its onset (pathological or exposure to causal agents) to its resolution. It is generally considered “natural” when no interventions are used that could affect the resolution process [1,2]. […]

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Advantages and Disadvantages of Research Metrics used to Evaluate a Researcher’s Impact or Influence

By: Chad E Cook PT, PhD, FAPTA Background: Each year, in Duke University’s Division of Physical Therapy, I teach a class on research methodology. One of the topics we discuss in class involves ways to measure research impact among physical therapists’ (and other professions’) researchers. The discussion is complimentary to those that occur during the […]

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“It’s Not You, It’s Us…”: Heterogeneity of Treatment Effects as a Challenge to Effectiveness Trials.

By: Damian L Keter, PT, DPT, PhD Background:   Comparative effectiveness studies are the cornerstone of medicine and health sciences research. They have a goal of finding ‘the best’ treatment for each associated condition. In comparative effectiveness studies, statistical models are able to provide ‘average’ treatment effects, which are often used to establish standardized mean difference […]

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Is Myofascial Pain Syndrome a Legitimate Primary Diagnosis?

By: Chad E Cook, Damian Keter, Ken Learman Background: Myofascial Pain Syndrome (MPS) is hypothesized to be both a primary and/or a secondary chronic pain disorder that can refer symptoms to other parts of the body. MPS is relatively common, affecting millions of people worldwide, particularly those who have experienced muscle overuse, trauma, or stress […]

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Risk of Bias Measures can be Biased

By: Chad E Cook, Damian Keter, Ken Learman Navigating the Literature: Navigating the ever-growing, healthcare literature can be challenging [1]. The sheer amount of new research, articles, and guidelines published regularly can be overwhelming. The number of biomedical publications has been steadily increasing over the years. As of 2022, there were approximately 3.3 million scientific […]

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Why Isn’t Everyone Using Stepped Care for Musculoskeletal Injuries? 

By: Chad E. Cook PT, PhD, FAPTA Resource efficiency models  Musculoskeletal (MSK) outcomes have shown some concerning trends over the last decade. Conditions like low back pain, neck pain, and joint pain have become more prevalent, contributing to the overall burden of a MSK disorder [1]. According to a report analyzing medical claims data from […]

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Three Ways That Recruitment in Randomized Controlled Trials May Not Reflect Real Life

By: Chad Cook, Amy McDevitt, Derek Clewley, Bryan O’Halloran As we wind up a year of recruitment on the SS-MECH trial [1], we are compelled to reflect on our recruitment strategies and study participants. Our study has included four recruitment sites and we’ve enrolled over 110 participants, which is nearly 85% of our targeted sample. […]

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