Week 2: An Interview with Dr. David Pickup

“I always have been intrigued by how things work.” Dr. Pickup replied as I asked him why he enjoyed being a researcher. He continued to explain that science is an avenue through which to understand how things work; particularly in his field of work, understanding virus and host cell interactions.

Dr. David Pickup first decided to pursue science in highschool; his school had students choose a course of study focused in either the sciences or the arts early on, and he chose to study science. He went on to receive a degree in Botany (specializing in microbiology) from Royal Holloway College, University of London in 1974. Through his study of botany, he learned of plant pathogens and plasmids, which caught his interest. In 1975, he received his Masters degree in General Virology from the University of Birmingham, United Kingdom. He then received his PhD in virology from the National Institute for Medical Research, London in 1979.

He received further training with molecular biology and poxviruses during his post-doctoral training at Duke University, in the Department of Microbiology and Immunology. Following his post-doc work, he joined Duke’s faculty and has since remained with the university as a researcher. His lab studies poxviruses and interactions between the host cell; particularly, he is fascinated by how poxviruses can control and manipulate host functions and immune responses. A deeper understanding of these mechanisms could prove useful for future applications, including some therapies or immunizations.

Dr. Pickup’s advice for anyone interested in pursuing a career in research is that they must have a passion for it. Research takes a tremendous amount of time and energy, and without a passion for it, it would be a very difficult field to be in. He suggests exploring a variety of fields in science and finding one that interests you; pursue research in an area that stimulates your interest. He also cautioned that research is often delayed gratification. It can take an extraordinary amount of  time and effort to reach a definitive answer in science; a research project could last several months or years. But with patience and a passion for their field of investigation, an individual can thrive in scientific research.

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