Representative Publications:
Walton EM, Cronan MR, Cambier CJ, Rossi A, Marass M, Foglia MD, Brewer WJ, Poss KD, Stainier DYR, Bertozzi CR, Tobin DM (2018). Cyclopropane modification of trehalose dimycolate drives granuloma angiogenesis and mycobacterial growth through Vegf signaling. Cell Host & Microbe 24:514-525.
Jain SK, Tobin DM, Tucker EW, Venketaraman V, Ordonez AA, Jayashankar L, Siddiqi OK, Hammoud DA, Prasadarao NV, Sandor M, Hafner R, Fabry Z; NIH Tuberculous Meningitis Writing Group (2018). Tuberculous meningitis: a roadmap for advancing basic and translational research. Nat Immunol 19:521-525.
Alvarez MI, Glover LC, Luo P, Wang L, Theusch E, Oehlers SH, Walton EM, Tram TTB, Kuang YL, Rotter JI, McClean CM, Chinh NT, Medina MW, Tobin DM, Dunstan SJ, Ko DC (2017). Human genetic variation in VAC14 regulates Salmonella invasion and typhoid fever through modulation of cholesterol. Proc Natl Acad Sci USA 114:E7746-E7755.
Oehlers SH, Cronan MR, Beerman RW, Johnson MG, Huang J, Kontos CD, Stout JE, Tobin DM (2017). Infection-induced vascular permeability aids mycobacterial growth. J Infect Dis 215:813-817.
Cronan MR, Beerman RW, Rosenberg AF, Saelens JW, Johnson MG, Oehlers SH, Sisk DM, Jurcic Smith KL, Medvitz NA, Miller SE, Trinh LA, Fraser SE, Madden JF, Turner J, Stout JE, Lee S, Tobin DM (2016). Macrophage epithelial reprogramming underlies mycobacterial granuloma formation and promotes infection. Immunity 45:861-76.
Beerman RW, Matty MA, Au GG, Looger LL, Choudhury KR, Keller PJ, Tobin DM (2015). Direct in vivo manipulation and imaging of calcium transients in neutrophils identifies a critical role for leading-edge calcium flux. Cell Reports 13:2107-17.
Cronan MR, Rosenberg AF, Oehlers SH, Saelens JW, Sisk DM, Smith KLJ, Lee S, Tobin DM (2015). CLARITY and PACT-based imaging of adult zebrafish and mouse for whole-animal analysis of infections. Dis Model Mech 8:1643-50.
Saelens JW, Lau-Bonilla D, Moller A, Medina N, Guzmán B, Calderón M, Herrera R, Sisk DM, Xet-Mull AM, Stout JE, Arathoon E, Samayoa B*, Tobin DM* (2015). Whole genome sequencing identifies circulating Beijing-lineage Mycobacterium tuberculosis strains in Guatemala and an associated urban outbreak. Tuberculosis 95:810-16.
Tenor J*, Oehlers SH*, Yang JL, Tobin DM**, Perfect JR** (2015). Live imaging of host-parasite interactions in a zebrafish infection model reveals cryptococcal determinants of virulence and central nervous system invasion. MBio 6(5) e01425-15. doi:10.1128/mBio.01425-15
Wang L, Oehlers SH, Espenschied ST, Rawls JF, Tobin DM, Ko DC (2015). CPAG: Software for leveraging pleiotropy in GWAS to reveal similarity between human traits links plasma fatty acids and intestinal inflammation. Genome Biology 16:190.
Tobin, DM. (2015). Host-Directed Therapies for Tuberculosis, Cold Spring Harb Perspect Med 5(10) pii: a021196. doi: 10.1101/cshperspect.a021196.
Oehlers SH, Cronan MR, Thomas MI, Okuda KS, Walton EM, Beerman RW, Crosier PS, Tobin DM (2015). Interception of host angiogenic signalling limits mycobacterial growth. Nature 517: 612-15.
Cambier CJ, Takaki KK, Larson RP, Hernandez RE, Tobin DM, Urdahl KB, Cosma CC, Ramakrishnan L (2014). Mycobacteria manipulate macrophage recruitment through coordinate use of membrane lipids. Nature 505(7482):218-22
Tobin DM, Roca FJ, Oh SF, McFarland R, Vickery TW, Ray JP, Ko DC, Zou Y, Bang ND, Chau TTH, Vary JC, Hawn TR, Dunstan SJ, Farrar JJ, Thwaites GE, King M-C, Serhan CN, Ramakrishnan L (2012). Genotype-specific therapies can optimize the inflammatory response to mycobacterial infections. Cell 148: 434-446.
Tobin DM, Vary JC, Ray JP, Walsh GS, Bang ND, Dunstan SJ, Hagge DA, Khadge S, King MC, Hawn TR, Moens CB, Ramakrishnan L. (2010). The lta4h locus modulates susceptibility to mycobacterial infection in zebrafish and humans. Cell 140(5):717-30.
For a complete list of publications, click here.
