The Department of Defense (DOD) has awarded Jung Wook Park, PhD, a $150,000 FY24 Exploration – Hypothesis Development Award. The grant will be disbursed for two years on September 1, 2025. Park plans to use the funds to define the biology of how prostate cancer progresses to become lethal. He hopes that his work will result in the creation of new preclinical human prostate cancer models, which would represent a significant leap forward in the field of cancer research and boost patient outcomes.
Recent studies demonstrate the potential for prostate adenocarcinoma (PrAd) to transform into neuroendocrine prostate cancer (NEPC) during current therapeutic treatments. Distinct characteristics of NEPC and PrAd necessitate different treatment strategies, and the coexistence of NEPC cells with PrAd cells underscores the critical need for effective treatment options that target both cancer types. Park’s study seeks to provide definitive insights into the intricate communication between NEPC and PrAd cells, shedding light on how they either collaborate or compete in their growth. Read more.