Sharing Knowledge: Noteworthy Publications
Sharing Knowledge: Noteworthy Publications
Sharing new knowledge with others in the scientific community helps to advance expertise and understanding about a particular disease and raise awareness of best practices and practical applications associated with treatments and interventions.
Through the publication of scientifically grounded research in peer-reviewed journals, clinicians and researchers disseminate this knowledge to others in the same field of study.
Duke CTSI supports investigators and research teams in this process of knowledge-sharing through a variety of means, including the publication of findings in high-quality journals. Review a sampling of CTSI-supported publications disseminated this past year.
“Development and evaluation of a novel training program to build study staff skills in equitable and inclusive engagement, recruitment, and retention of clinical research participants” | Journal of Clinical and Translational Science
The Duke Engagement, Recruitment, and Retention Certificate Program was featured in a publication that focused on the development of the program and evaluated its impact on clinical research participant recruitment. The Duke CTSI Recruitment Innovation Center (RIC) helps manage this certificate program, and CTSI leaders Susanna Naggie, MD, MHS, FIDSA, and Nadine J. Barrett, PhD, were authors on the paper.
“Moving beyond annual data reports: A blueprint for communicating and disseminating actionable intelligence” | Journal of Clinical and Translational Science
Duke CTSI Equity and Learning Health Communities Pillar Co-Director Raquel Ruiz, MBA, MA Ed, co-authored a special communication on the coupling of qualitative and quantitative data.
“From insights to action: Enriching the clinical and translational research workforce by developing diverse and inclusive career programs” | Journal of Clinical and Translational Science
Duke CTSI Equity and Learning Health Communities Pillar Co-Director Raquel Ruiz, MBA, MA Ed, co-authored a special communication on the methodology employed for engaging CTSAs to identify and articulate their strategies to enhance the diversity of scientists within the field of translational science.
“The Cabarrus County COVID-19 Prevalence and Immunity (C3PI) Study: design, methods, and baseline characteristics” | American Journal of Translational Research
A partnership with the CTSI, N.C. Department of Health and Human Services, and the Kannapolis and Cabarrus County community, this COVID-19 research project contributed valuable information on prevalence of COVID infection and SARS-CoV-2 antibodies. The publication describes the study design and methods and highlights exceptional implementation work by the Duke Kannapolis team.
“Comparison of a Blood Self-Collection System with Routine Phlebotomy for SARS-CoV-2 Antibody Testing” | Diagnostics
In a Duke Kannapolis pilot study within the MURDOCK Cabarrus County COVID-19 Prevalence and Immunity (C3PI) project, a comparison of blood samples self-collected by participants and those collected by study staff found the differences in antibody test results were not significant, indicating that assay sensitivity using the device specimen was equivalent to that using routine phlebotomy.
“A method for intelligent allocation of diagnostic testing by leveraging data from commercial wearable devices: a case study on COVID-19” | Nature Digital Medicine
In the first major paper on study findings from CovIdentify, the CTSI and Duke Kannapolis are acknowledged for contributions to the COVID-19 research project. The article thanks Julie Eckstrand, RPh, the Duke Kannapolis Director of Operations, and Cecilia Plez, Research Program Leader, and acknowledges the CTSI, which provided funding for the project. Duke Kannapolis recruited for CovIdentify through two community registries and translated all study materials so the study could recruit, consent, and enroll in Spanish. Led by Jessilyn Dunn, PhD, and Ryan Shaw, PhD with the Duke BIG IDEAs Lab, CovIdentify is about detecting COVID-19 infection with wearable devices.
“Creating a racial justice plan in a school of nursing: A journey of discovery and learning” | Journal of Professional Nursing
Diane Uzarski, DNP, NPH, RN, Senior Staff Director of Strategy and Planning at Duke CTSI, co-authored a publication outlining ways to address racism and white supremacy-based policies and practices in the Duke University School of Nursing.
“Issues for recruitment and retention of clinical research professionals at academic medical centers: Part 1 – collaborative conversations Un-Meeting findings” | Journal of Clinical and Translational Science
Members of the CTSI Workforce Development team are featured in this paper about recruitment and retention of clinical research professionals.
“Academic medical center clinical research professional workforce: Part 2 – Issues in staff onboarding and professional development” | Journal of Clinical and Translational Science
Members of the CTSI Workforce Development team are featured in this paper about issues in staff onboarding and professional development.
“Adaptive stress response genes associated with breast cancer subtypes and survival outcomes reveal race-related differences” | npj Breast Cancer
Chronically stressful conditions of daily life such as racism, pollution, and poverty have a direct impact on the cellular mechanisms that drive lethal, invasive forms of breast cancer, according to a study led by Duke Cancer Institute researchers. Gayathri Devi, PhD, Director of the Duke-NCCU Bridge Office, is the senior author on this publication.
“The Use of the Ethno-Drama Experience to Increase Knowledge and Promote Cervical Cancer Health Related Behavior among People of Color” | Journal of Cervical Cancer Research
Research team members at NCCU were published in an article highlighting the Duke-NCCU partnership on ethnodramas in clinical research, focusing primarily on a production about cervical cancer.
“Multi-dimensional characterization of prediabetes in the Project Baseline Health Study” | Cardiovascular Diabetology
Project Baseline Health Study participants with prediabetes demonstrated changes in cardiac, pulmonary, and hematology measures, as well as declines in physical function and sleep, that precede diabetes. Some of these changes over four years of follow-up predicted an increased risk of progression to diabetes. Duke CTSI enrolled more than 1,000 Baseline Health Study participants in Durham and Kannapolis.
Volume III in the Interdisciplinary Community-Engaged Research for Health series, “Engaging the Intersection of Housing and Health,” was edited and co-authored by CERI Director Mina Silberberg, PhD. Each volume in the series highlights case studies of research that is interdisciplinary, stakeholder-engaged, and intentionally designed for translation into practice.
“The Watershed Of Practice-Based Research: Lessons And Opportunities From The COVID Pandemic” | Health Affairs
The article discusses the impact of the COVID pandemic on practice-based research network research, especially in rural/medical underserved areas where primary care clinics closed due to lack of financial resources. This article highlights the need to expand funding for the Primary Care Research Infrastructure, fund a federal hub for Primary Care Research, and increase patient-centered outcomes research directed toward primary care research.
“Combating Structural Inequities — Diversity, Equity, and Inclusion in Clinical and Translational Research” | The New England Journal of Medicine
Dr. L. Ebony Boulware, Director of Duke CTSI, is the first author on a perspective, arguing that for “the clinical and translational research enterprise to help resolve current and future health crises…it must shift paradigms and begin to center diversity, equity, and inclusion in its work.”
“The U.S. needs to engage communities around BIPOC data,” | STAT
Warren Kibbe, PhD, Director of the Bioinformatics Core, co-authored an opinion piece for STAT News about how a lack of data about BIPOC communities contributes to health inequities.
“Profiling serum neurofilament light chain and glial fibrillary acidic protein in primary progressive multiple sclerosis” | Journal of Neuroimmunology
In a study recruited through the MURDOCK Study at Duke Kannapolis, findings from of an examination of the utility of serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) as biomarkers in primary progressive multiple sclerosis suggest a limited role in disease management.
“Experiences of Family Caregivers of People with Dementia during the COVID-19 Pandemic” | Western Journal of Nursing Research
A new study found that the pandemic amplified feelings of loss, isolation, and stress, and intensified challenges experienced by families living with dementia. Melissa Harris, PhD, RN, a Duke National Clinician Scholars Program scholar, led the study at the University of Michigan during her doctoral training.
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