Our lab is equipped with advanced instrumentation to support high-quality cryo-electron microscopy (cryo-EM) research and data analysis:
Sample Preparation:
We utilize Leica Microsystems plunge freezers for consistent and reliable vitrification of cryo-EM grids.
In-House Instrumentation:
A dedicated 100 kV Tundra Cryo-TEM (Thermo Fisher Scientific) equipped with a Falcon C direct electron detector, enables in-house grid screening and preliminary data collection.
High-Resolution Data Collection:
For advanced structural studies, we have access to a 300 kV Titan Krios (Thermo Fisher Scientific) equipped with a Gatan K3 detector, available through Duke University’s shared cryo-EM facilities.
Computational Resources:
We maintain high-performance workstations optimized for cryo-EM data processing, supported by a dedicated server infrastructure for robust data storage and computational workflow management.
